Recent progress and perspectives of continuous in vivo testing device
Devices for continuous in-vivo testing (CIVT) can detect target substances in real time, thus providing a valuable window into a patient's condition, their response to therapeutics, metabolic activities, and neurotransmitter transmission in the brain. Therefore, CIVT devices have received incre...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Materials Today Bio |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006422001399 |
| _version_ | 1828142751066095616 |
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| author | Tao Ming Jinping Luo Yu Xing Yan Cheng Juntao Liu Shuai Sun Fanli Kong Shihong Xu Yuchuan Dai Jingyu Xie Hongyan Jin Xinxia Cai |
| author_facet | Tao Ming Jinping Luo Yu Xing Yan Cheng Juntao Liu Shuai Sun Fanli Kong Shihong Xu Yuchuan Dai Jingyu Xie Hongyan Jin Xinxia Cai |
| author_sort | Tao Ming |
| collection | DOAJ |
| description | Devices for continuous in-vivo testing (CIVT) can detect target substances in real time, thus providing a valuable window into a patient's condition, their response to therapeutics, metabolic activities, and neurotransmitter transmission in the brain. Therefore, CIVT devices have received increased attention because they are expected to greatly assist disease diagnosis and treatment and research on human pathogenesis. However, CIVT has been achieved for only a few markers, and it remains challenging to detect many key markers. Therefore, it is important to summarize the key technologies and methodologies of CIVT, and to examine the direction of future development of CIVT. We review recent progress in the development of CIVT devices, with consideration of the structure of these devices, principles governing continuous detection, and nanomaterials used for electrode modification. This detailed and comprehensive review of CIVT devices serves three purposes: (1) to summarize the advantages and disadvantages of existing devices, (2) to provide a reference for development of CIVT equipment to detect additional important markers, and (3) to discuss future prospects with emphasis on problems that must be overcome for further development of CIVT equipment. This review aims to promote progress in research on CIVT devices and contribute to future innovation in personalized medical treatments. |
| first_indexed | 2024-04-11T19:47:04Z |
| format | Article |
| id | doaj.art-7587a14ac28e47538faa3fa31bce420a |
| institution | Directory Open Access Journal |
| issn | 2590-0064 |
| language | English |
| last_indexed | 2024-04-11T19:47:04Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj.art-7587a14ac28e47538faa3fa31bce420a2022-12-22T04:06:27ZengElsevierMaterials Today Bio2590-00642022-12-0116100341Recent progress and perspectives of continuous in vivo testing deviceTao Ming0Jinping Luo1Yu Xing2Yan Cheng3Juntao Liu4Shuai Sun5Fanli Kong6Shihong Xu7Yuchuan Dai8Jingyu Xie9Hongyan Jin10Xinxia Cai11Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaAerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaAerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaObstetrics and Gynecology Department, Peking University First Hospital, Beijing, 100034, PR ChinaAerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaAerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaAerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaAerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaAerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaAerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, ChinaObstetrics and Gynecology Department, Peking University First Hospital, Beijing, 100034, PR China; Corresponding author.Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China; School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China; Corresponding author. Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, 100094, PR China.Devices for continuous in-vivo testing (CIVT) can detect target substances in real time, thus providing a valuable window into a patient's condition, their response to therapeutics, metabolic activities, and neurotransmitter transmission in the brain. Therefore, CIVT devices have received increased attention because they are expected to greatly assist disease diagnosis and treatment and research on human pathogenesis. However, CIVT has been achieved for only a few markers, and it remains challenging to detect many key markers. Therefore, it is important to summarize the key technologies and methodologies of CIVT, and to examine the direction of future development of CIVT. We review recent progress in the development of CIVT devices, with consideration of the structure of these devices, principles governing continuous detection, and nanomaterials used for electrode modification. This detailed and comprehensive review of CIVT devices serves three purposes: (1) to summarize the advantages and disadvantages of existing devices, (2) to provide a reference for development of CIVT equipment to detect additional important markers, and (3) to discuss future prospects with emphasis on problems that must be overcome for further development of CIVT equipment. This review aims to promote progress in research on CIVT devices and contribute to future innovation in personalized medical treatments.http://www.sciencedirect.com/science/article/pii/S2590006422001399NanomaterialIn-vivo testingMicrofluidic chipContinuous detection equipmentAptamer |
| spellingShingle | Tao Ming Jinping Luo Yu Xing Yan Cheng Juntao Liu Shuai Sun Fanli Kong Shihong Xu Yuchuan Dai Jingyu Xie Hongyan Jin Xinxia Cai Recent progress and perspectives of continuous in vivo testing device Materials Today Bio Nanomaterial In-vivo testing Microfluidic chip Continuous detection equipment Aptamer |
| title | Recent progress and perspectives of continuous in vivo testing device |
| title_full | Recent progress and perspectives of continuous in vivo testing device |
| title_fullStr | Recent progress and perspectives of continuous in vivo testing device |
| title_full_unstemmed | Recent progress and perspectives of continuous in vivo testing device |
| title_short | Recent progress and perspectives of continuous in vivo testing device |
| title_sort | recent progress and perspectives of continuous in vivo testing device |
| topic | Nanomaterial In-vivo testing Microfluidic chip Continuous detection equipment Aptamer |
| url | http://www.sciencedirect.com/science/article/pii/S2590006422001399 |
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