A simplified multiplex methylated DNA testing for early detection of colorectal cancer in stool DNA

A simplified multiplex methylated DNA testing for early detection of colorectal cancer in stool DNA

Abstract Background ColoDefense1.0 assay has demonstrated its excellent sensitivity and specificity for early detection of colorectal cancer (CRC) by detecting the methylation levels of SDC2 and SEPT9, while exhibited limitations on relatively large sample capacity required and limited detection thr...

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Bibliographic Details
Main Authors: Yanmiao Dai, Guodong Zhao, Jun Yang, Xilang Zhou, Shangmin Xiong, Xirong Lu, Liming Gao, Jianfang Wu, Zouhua Xu, Sujuan Fei, Minxue Zheng, Hongwei Xu
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Gastroenterology
Subjects:
Colorectal cancer
Early detection
Stool
Simplified
DNA methylation
Online Access:https://doi.org/10.1186/s12876-022-02512-6

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