Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional Study
Takafumi Saito,1 Xin Liu,2 Harukaze Yatsugi,3 Tianshu Chu,2 Tsubasa Yokote,2 Hiro Kishimoto2,3 1Faculty of Rehabilitation, School of Physical Therapy, Reiwa Health Sciences University, Fukuoka, Japan; 2Graduate School of Human-Environment Studies, Kyushu University, Fukuoka, Japan; 3Faculty of Arts...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-08-01
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| Series: | Journal of Pain Research |
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| Online Access: | https://www.dovepress.com/relationship-between-chronic-pain-types-nociceptive-and-neuropathic-li-peer-reviewed-fulltext-article-JPR |
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| author | Saito T Liu X Yatsugi H Chu T Yokote T Kishimoto H |
| author_facet | Saito T Liu X Yatsugi H Chu T Yokote T Kishimoto H |
| author_sort | Saito T |
| collection | DOAJ |
| description | Takafumi Saito,1 Xin Liu,2 Harukaze Yatsugi,3 Tianshu Chu,2 Tsubasa Yokote,2 Hiro Kishimoto2,3 1Faculty of Rehabilitation, School of Physical Therapy, Reiwa Health Sciences University, Fukuoka, Japan; 2Graduate School of Human-Environment Studies, Kyushu University, Fukuoka, Japan; 3Faculty of Arts and Science, Kyushu University, Fukuoka, JapanCorrespondence: Hiro Kishimoto, Faculty of Arts and Science, Kyushu University, IC15, 744 Motooka, Nishi-ku, Fukuoka City, Fukuoka, 819-0395, Japan, Tel +81-92-802-6071, Email kishimoto@artsci.kyushu-u.ac.jpPurpose: Chronic pain may accelerate the development of frailty in older adults through a variety of mechanisms. There are no published investigations of the influence of neuropathic-like symptoms on physical frailty. We investigated the association between chronic pain types (nociceptive and neuropathic-like symptoms) and frailty in community-dwelling Japanese older adults.Participants and Methods: This was a population-based cross-sectional study conducted in 2017 in the city of Itoshima, Japan of 917 participants aged 65– 75 years, not in need of long-term care, who had completed the physical function tests and questionnaires administered at measurement sessions held at community centers at three sites over a 1- to 2-month period. Their chronic pain types were classified as no-chronic pain, nociceptive pain, and neuropathic-like symptoms according to their painDETECT scores. Frailty phenotypes were defined by the following five components: unintentional weight loss, low grip strength, exhaustion, slow gait speed, and low physical activity. A logistic regression model was used to compute the odds ratios (ORs) and 95% confidence interval (CIs) for frailty status outcomes.Results: The prevalence of pre-frailty was 51.9%, and that of frailty was 5.1%. In multinomial logistic regression analyses, compared to the no-chronic pain group, the OR for the presence of pre-frailty among the participants with nociceptive pain was 1.54 (95% CI: 1.04– 2.30, p=0.03), and the OR for the presence of frailty among the participants with neuropathic-like symptoms was 4.37 (95% CI: 1.10– 17.37, p=0.04). The neuropathic sensory symptoms of burning, tingling/prickling, and numbness were each associated with frailty, but not with the risk of pre-frailty.Conclusion: Neuropathic-like symptoms were significantly associated with the presence of frailty in community-dwelling Japanese older adults. Chronic pain types might have different effects on frailty status.Keywords: nociceptive pain, neuropathic pain, nociceptive pain, chronic pain, frailty, community-dwelling |
| first_indexed | 2024-03-12T20:32:20Z |
| format | Article |
| id | doaj.art-758902e799344d1d9afc999c048cad65 |
| institution | Directory Open Access Journal |
| issn | 1178-7090 |
| language | English |
| last_indexed | 2024-03-12T20:32:20Z |
| publishDate | 2023-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Pain Research |
| spelling | doaj.art-758902e799344d1d9afc999c048cad652023-08-01T19:38:38ZengDove Medical PressJournal of Pain Research1178-70902023-08-01Volume 162675268485569Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional StudySaito TLiu XYatsugi HChu TYokote TKishimoto HTakafumi Saito,1 Xin Liu,2 Harukaze Yatsugi,3 Tianshu Chu,2 Tsubasa Yokote,2 Hiro Kishimoto2,3 1Faculty of Rehabilitation, School of Physical Therapy, Reiwa Health Sciences University, Fukuoka, Japan; 2Graduate School of Human-Environment Studies, Kyushu University, Fukuoka, Japan; 3Faculty of Arts and Science, Kyushu University, Fukuoka, JapanCorrespondence: Hiro Kishimoto, Faculty of Arts and Science, Kyushu University, IC15, 744 Motooka, Nishi-ku, Fukuoka City, Fukuoka, 819-0395, Japan, Tel +81-92-802-6071, Email kishimoto@artsci.kyushu-u.ac.jpPurpose: Chronic pain may accelerate the development of frailty in older adults through a variety of mechanisms. There are no published investigations of the influence of neuropathic-like symptoms on physical frailty. We investigated the association between chronic pain types (nociceptive and neuropathic-like symptoms) and frailty in community-dwelling Japanese older adults.Participants and Methods: This was a population-based cross-sectional study conducted in 2017 in the city of Itoshima, Japan of 917 participants aged 65– 75 years, not in need of long-term care, who had completed the physical function tests and questionnaires administered at measurement sessions held at community centers at three sites over a 1- to 2-month period. Their chronic pain types were classified as no-chronic pain, nociceptive pain, and neuropathic-like symptoms according to their painDETECT scores. Frailty phenotypes were defined by the following five components: unintentional weight loss, low grip strength, exhaustion, slow gait speed, and low physical activity. A logistic regression model was used to compute the odds ratios (ORs) and 95% confidence interval (CIs) for frailty status outcomes.Results: The prevalence of pre-frailty was 51.9%, and that of frailty was 5.1%. In multinomial logistic regression analyses, compared to the no-chronic pain group, the OR for the presence of pre-frailty among the participants with nociceptive pain was 1.54 (95% CI: 1.04– 2.30, p=0.03), and the OR for the presence of frailty among the participants with neuropathic-like symptoms was 4.37 (95% CI: 1.10– 17.37, p=0.04). The neuropathic sensory symptoms of burning, tingling/prickling, and numbness were each associated with frailty, but not with the risk of pre-frailty.Conclusion: Neuropathic-like symptoms were significantly associated with the presence of frailty in community-dwelling Japanese older adults. Chronic pain types might have different effects on frailty status.Keywords: nociceptive pain, neuropathic pain, nociceptive pain, chronic pain, frailty, community-dwellinghttps://www.dovepress.com/relationship-between-chronic-pain-types-nociceptive-and-neuropathic-li-peer-reviewed-fulltext-article-JPRnociceptive painneuropathic painnociceptive painchronic painfrailtycommunity-dwelling |
| spellingShingle | Saito T Liu X Yatsugi H Chu T Yokote T Kishimoto H Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional Study Journal of Pain Research nociceptive pain neuropathic pain nociceptive pain chronic pain frailty community-dwelling |
| title | Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional Study |
| title_full | Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional Study |
| title_fullStr | Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional Study |
| title_full_unstemmed | Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional Study |
| title_short | Relationship Between Chronic Pain Types (Nociceptive and Neuropathic-Like Symptoms) and Frailty in Community-Dwelling Japanese Older Adults: A Cross-Sectional Study |
| title_sort | relationship between chronic pain types nociceptive and neuropathic like symptoms and frailty in community dwelling japanese older adults a cross sectional study |
| topic | nociceptive pain neuropathic pain nociceptive pain chronic pain frailty community-dwelling |
| url | https://www.dovepress.com/relationship-between-chronic-pain-types-nociceptive-and-neuropathic-li-peer-reviewed-fulltext-article-JPR |
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