Sinusoidal CO2 respiratory challenge for concurrent perfusion and cerebrovascular reactivity MRI

Sinusoidal CO2 respiratory challenge for concurrent perfusion and cerebrovascular reactivity MRI

Introduction: Deoxygenation-based dynamic susceptibility contrast (dDSC) has previously leveraged respiratory challenges to modulate blood oxygen content as an endogenous source of contrast alternative to gadolinium injection in perfusion-weighted MRI. This work proposed the use of sinusoidal modula...

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Bibliographic Details
Main Authors: Chau Vu, Botian Xu, Clio González-Zacarías, Jian Shen, Koen P. A. Baas, Soyoung Choi, Aart J. Nederveen, John C. Wood
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Physiology
Subjects:
brain perfusion
respiratory challenges
cerebrovascular reactivity (CVR)
carbon dioxide challenge
deoxygenation
dynamic susceptibility contrast (DSC)
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1102983/full

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