Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection

Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection

Abstract Background The recent rise and spread of carbapenem-resistant pathogens pose an urgent threat to public health and has fueled the search for new therapies. Localized delivery of topical antibiotics is an alternative for the treatment of infected wounds caused by drug-resistant pathogens. In...

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Bibliographic Details
Main Authors: Sun Hee Moon, Yihong Kaufmann, Ryoichi Fujiwara, En Huang
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Microbiology
Subjects:
Carbapenem-resistance
Wound infection
Paenipeptin
Clarithromycin
Hydrogel
Online Access:https://doi.org/10.1186/s12866-021-02383-z

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