Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study

The purpose of the present study was to document pathological findings on retromode imaging in choroidal nevi and evaluate its diagnostic validity, using the confocal scanning laser ophthalmoscope Nidek Mirante (cSLO). A total of 41 choroidal nevi from 41 patients were included. All patients underwe...

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Main Authors: Claudia Azzolini, Maura Di Nicola, Francesco Pozzo Giuffrida, Francesca Cappelli, Claudia Bellina, Francesco Viola, Paolo Chelazzi
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/6/1253
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author Claudia Azzolini
Maura Di Nicola
Francesco Pozzo Giuffrida
Francesca Cappelli
Claudia Bellina
Francesco Viola
Paolo Chelazzi
author_facet Claudia Azzolini
Maura Di Nicola
Francesco Pozzo Giuffrida
Francesca Cappelli
Claudia Bellina
Francesco Viola
Paolo Chelazzi
author_sort Claudia Azzolini
collection DOAJ
description The purpose of the present study was to document pathological findings on retromode imaging in choroidal nevi and evaluate its diagnostic validity, using the confocal scanning laser ophthalmoscope Nidek Mirante (cSLO). A total of 41 choroidal nevi from 41 patients were included. All patients underwent multicolor fundus (mCF), infrared reflectance (IR), green fundus autofluorescence (FAF), dark-field (DF) and retromode (RM) imaging and optical coherence tomography (OCT) scans. We investigated retromode images to evaluate choroidal nevus features by comparing the results with those of mCF, IR, FAF, DF and OCT. In 100% of available images, retromode scanning laser ophthalmoscopy was able to detect choroidal nevi with a characteristic “hypo-retro-reflective” pattern, even the cases not visible on mCF, IR and FAF images. It also made it possible to delineate the margins of lesions with the highest rate of sharpness and accuracy among the imaging modalities examined. These findings seem to demonstrate how RM-SLO is an innovative diagnostic tool to detect and follow up choroidal nevi in a fast, reliable and non-invasive way.
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spelling doaj.art-758f26786535477a8e21ec3dab324a502023-11-18T11:16:44ZengMDPI AGLife2075-17292023-05-01136125310.3390/life13061253Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary StudyClaudia Azzolini0Maura Di Nicola1Francesco Pozzo Giuffrida2Francesca Cappelli3Claudia Bellina4Francesco Viola5Paolo Chelazzi6Department of Ophthalmology, Istituto Clinico Città Studi, 20131 Milan, ItalyDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami 33136, FL, USADepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalyDepartment of Ophthalmology, Istituto Clinico Città Studi, 20131 Milan, ItalyDepartment of Ophthalmology, Istituto Clinico Città Studi, 20131 Milan, ItalyDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalyDepartment of Ophthalmology, Istituto Clinico Città Studi, 20131 Milan, ItalyThe purpose of the present study was to document pathological findings on retromode imaging in choroidal nevi and evaluate its diagnostic validity, using the confocal scanning laser ophthalmoscope Nidek Mirante (cSLO). A total of 41 choroidal nevi from 41 patients were included. All patients underwent multicolor fundus (mCF), infrared reflectance (IR), green fundus autofluorescence (FAF), dark-field (DF) and retromode (RM) imaging and optical coherence tomography (OCT) scans. We investigated retromode images to evaluate choroidal nevus features by comparing the results with those of mCF, IR, FAF, DF and OCT. In 100% of available images, retromode scanning laser ophthalmoscopy was able to detect choroidal nevi with a characteristic “hypo-retro-reflective” pattern, even the cases not visible on mCF, IR and FAF images. It also made it possible to delineate the margins of lesions with the highest rate of sharpness and accuracy among the imaging modalities examined. These findings seem to demonstrate how RM-SLO is an innovative diagnostic tool to detect and follow up choroidal nevi in a fast, reliable and non-invasive way.https://www.mdpi.com/2075-1729/13/6/1253choroidal nevusretromodemultimodal imagingscanning laser ophthalmoscopy
spellingShingle Claudia Azzolini
Maura Di Nicola
Francesco Pozzo Giuffrida
Francesca Cappelli
Claudia Bellina
Francesco Viola
Paolo Chelazzi
Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study
Life
choroidal nevus
retromode
multimodal imaging
scanning laser ophthalmoscopy
title Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study
title_full Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study
title_fullStr Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study
title_full_unstemmed Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study
title_short Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study
title_sort retromode scanning laser ophthalmoscopy for choroidal nevi a preliminary study
topic choroidal nevus
retromode
multimodal imaging
scanning laser ophthalmoscopy
url https://www.mdpi.com/2075-1729/13/6/1253
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AT francescacappelli retromodescanninglaserophthalmoscopyforchoroidalneviapreliminarystudy
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