Color Doppler Ultrasonography in Mapping Oral Squamous Cell Carcinoma
Background: Although Color Doppler Ultrasonography (CDUS) is useful in the diagnosis of various diseases of the head and neck, flow signals in oral malignant masses are less studied; hence the present study assesses the usefulness of Color Doppler Ultrasonography in quantifying oral squamous cell...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2015-07-01
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| Series: | Middle East Journal of Cancer |
| Subjects: | |
| Online Access: | http://mejc.sums.ac.ir/index.php/mejc/article/view/308/223 |
| _version_ | 1818759257622839296 |
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| author | Rahul Gandhi Abhishek Singh Nayyar Rahul Bhowate Sweta Gandhi Girish Dongerwar |
| author_facet | Rahul Gandhi Abhishek Singh Nayyar Rahul Bhowate Sweta Gandhi Girish Dongerwar |
| author_sort | Rahul Gandhi |
| collection | DOAJ |
| description | Background: Although Color Doppler Ultrasonography (CDUS) is useful in the
diagnosis of various diseases of the head and neck, flow signals in oral malignant masses
are less studied; hence the present study assesses the usefulness of Color Doppler Ultrasonography
in quantifying oral squamous cell carcinoma (OSCC) vascularization. In
addition, we determine the hemodynamic parameters by spectral analysis obtained during
a Color Doppler Ultrasonography procedure. We have studied the usefulness of Color
Doppler Ultrasonography in mapping oral squamous cell carcinoma of the buccal
mucosa, tongue and lip.
Methods: This case-control study enrolled 60 subjects aged 20-70 years. Group A
constituted 30 cases diagnosed with oral squamous cell carcinoma and Group B
constituted 30 healthy controls. Ultrasonographic investigation of each mass was
performed. The spectral waveform (time-velocity Doppler spectrum) of the flow
signal was analyzed for the pulsatility index, resistive index, peak systolic velocity
(m/sec), and end diastolic velocity (m/sec). All patients had real-time, gray-scale
sonography and Color Doppler Ultrasonography with spectral wave analysis.
Results: The mean value for the resistive index in patients with oral squamous cell
carcinoma was 0.40±0.14 whereas for healthy subjects, it was 0.83±0.07. The mean
pulsatility index value in malignant patients was 0.86±0.20 while for healthy subjects,
it came-out to be 2.61±0.77.
Conclusion: These Doppler indices have been shown to be sensitive and specific
for the diagnosis of malignant oral tumors. Although Color Doppler Ultrasonography
cannot replace histopathological procedures, it plays a definite role as an adjunct to
clinical evaluation of oral squamous cell carcinoma patients. |
| first_indexed | 2024-12-18T06:39:51Z |
| format | Article |
| id | doaj.art-759518fcf65645c595372473ca17e287 |
| institution | Directory Open Access Journal |
| issn | 2008-6709 2008-6687 |
| language | English |
| last_indexed | 2024-12-18T06:39:51Z |
| publishDate | 2015-07-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Middle East Journal of Cancer |
| spelling | doaj.art-759518fcf65645c595372473ca17e2872022-12-21T21:17:41ZengShiraz University of Medical SciencesMiddle East Journal of Cancer2008-67092008-66872015-07-0163179187Color Doppler Ultrasonography in Mapping Oral Squamous Cell CarcinomaRahul Gandhi0Abhishek Singh Nayyar1Rahul Bhowate2Sweta Gandhi3Girish Dongerwar4Department of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Parbhani, Maharashtra, IndiaDepartment of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Parbhani, Maharashtra, IndiaDepartment of Oral Medicine and Radiology, Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, IndiaDepartment of Public Health Dentistry, Lata Mangeshkar Dental College and Hospital, Nagpur, Maharashtra, IndiaDepartment of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Parbhani, Maharashtra, IndiaBackground: Although Color Doppler Ultrasonography (CDUS) is useful in the diagnosis of various diseases of the head and neck, flow signals in oral malignant masses are less studied; hence the present study assesses the usefulness of Color Doppler Ultrasonography in quantifying oral squamous cell carcinoma (OSCC) vascularization. In addition, we determine the hemodynamic parameters by spectral analysis obtained during a Color Doppler Ultrasonography procedure. We have studied the usefulness of Color Doppler Ultrasonography in mapping oral squamous cell carcinoma of the buccal mucosa, tongue and lip. Methods: This case-control study enrolled 60 subjects aged 20-70 years. Group A constituted 30 cases diagnosed with oral squamous cell carcinoma and Group B constituted 30 healthy controls. Ultrasonographic investigation of each mass was performed. The spectral waveform (time-velocity Doppler spectrum) of the flow signal was analyzed for the pulsatility index, resistive index, peak systolic velocity (m/sec), and end diastolic velocity (m/sec). All patients had real-time, gray-scale sonography and Color Doppler Ultrasonography with spectral wave analysis. Results: The mean value for the resistive index in patients with oral squamous cell carcinoma was 0.40±0.14 whereas for healthy subjects, it was 0.83±0.07. The mean pulsatility index value in malignant patients was 0.86±0.20 while for healthy subjects, it came-out to be 2.61±0.77. Conclusion: These Doppler indices have been shown to be sensitive and specific for the diagnosis of malignant oral tumors. Although Color Doppler Ultrasonography cannot replace histopathological procedures, it plays a definite role as an adjunct to clinical evaluation of oral squamous cell carcinoma patients.http://mejc.sums.ac.ir/index.php/mejc/article/view/308/223Oral cancerColor Doppler UltrasonographyPulsatility indexResistivity index |
| spellingShingle | Rahul Gandhi Abhishek Singh Nayyar Rahul Bhowate Sweta Gandhi Girish Dongerwar Color Doppler Ultrasonography in Mapping Oral Squamous Cell Carcinoma Middle East Journal of Cancer Oral cancer Color Doppler Ultrasonography Pulsatility index Resistivity index |
| title | Color Doppler Ultrasonography in Mapping Oral Squamous Cell Carcinoma |
| title_full | Color Doppler Ultrasonography in Mapping Oral Squamous Cell Carcinoma |
| title_fullStr | Color Doppler Ultrasonography in Mapping Oral Squamous Cell Carcinoma |
| title_full_unstemmed | Color Doppler Ultrasonography in Mapping Oral Squamous Cell Carcinoma |
| title_short | Color Doppler Ultrasonography in Mapping Oral Squamous Cell Carcinoma |
| title_sort | color doppler ultrasonography in mapping oral squamous cell carcinoma |
| topic | Oral cancer Color Doppler Ultrasonography Pulsatility index Resistivity index |
| url | http://mejc.sums.ac.ir/index.php/mejc/article/view/308/223 |
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