Impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno-arterial extracorporeal membrane oxygenation
Abstract Background Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) requires a large amount of economic and human resources. The presence of bystander cardiopulmonary resuscitation (CPR) was focused on selecting appropriate V-A ECMO candidates. Result This study retrospectively enrolled...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-02-01
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| Series: | International Journal of Emergency Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12245-023-00485-1 |
| _version_ | 1827985256033026048 |
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| author | Ryosuke Shimai Shohei Ouchi Tetsuro Miyazaki Koji Hirabayashi Hiroshi Abe Kosuke Yabe Midori Kakihara Masaaki Maki Hiroyuki Isogai Takeshi Wada Dai Ozaki Yuki Yasuda Fuminori Odagiri Kazuhisa Takamura Kenji Yaginuma Ken Yokoyama Takashi Tokano Tohru Minamino |
| author_facet | Ryosuke Shimai Shohei Ouchi Tetsuro Miyazaki Koji Hirabayashi Hiroshi Abe Kosuke Yabe Midori Kakihara Masaaki Maki Hiroyuki Isogai Takeshi Wada Dai Ozaki Yuki Yasuda Fuminori Odagiri Kazuhisa Takamura Kenji Yaginuma Ken Yokoyama Takashi Tokano Tohru Minamino |
| author_sort | Ryosuke Shimai |
| collection | DOAJ |
| description | Abstract Background Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) requires a large amount of economic and human resources. The presence of bystander cardiopulmonary resuscitation (CPR) was focused on selecting appropriate V-A ECMO candidates. Result This study retrospectively enrolled 39 patients with V-A ECMO due to out-of-hospital cardiac arrest (CA) between January 2010 and March 2019. The introduction criteria of V-A ECMO included the following: (1) < 75 years old, (2) CA on arrival, (3) < 40 min from CA to hospital arrival, (4) shockable rhythm, and (5) good activity of daily living (ADL). The prescribed introduction criteria were not met by 14 patients, but they were introduced to V-A ECMO at the discretion of their attending physicians and were also included in the analysis. Neurological prognosis at discharge was defined using The Glasgow-Pittsburgh Cerebral Performance and Overall Performance Categories of Brain Function (CPC). Patients were divided into good or poor neurological prognosis (CPC ≤ 2 or ≥ 3) groups (8 vs. 31 patients). The good prognosis group had a significantly larger number of patients who received bystander CPR (p = 0.04). The mean CPC at discharge was compared based on the combination with the presence of bystander CPR and all five original criteria. Patients who received bystander CPR and met all original five criteria showed significantly better CPC than patients who did not receive bystander CPR and did not meet some of the original five criteria (p = 0.046). Conclusion Considering the presence of bystander CPR help in selecting the appropriate candidate of V-A ECMO among out-of-hospital CA cases. |
| first_indexed | 2024-04-09T23:12:00Z |
| format | Article |
| id | doaj.art-759ca04afcea4d678b663a1fd82cb508 |
| institution | Directory Open Access Journal |
| issn | 1865-1380 |
| language | English |
| last_indexed | 2024-04-09T23:12:00Z |
| publishDate | 2023-02-01 |
| publisher | BMC |
| record_format | Article |
| series | International Journal of Emergency Medicine |
| spelling | doaj.art-759ca04afcea4d678b663a1fd82cb5082023-03-22T10:20:29ZengBMCInternational Journal of Emergency Medicine1865-13802023-02-011611610.1186/s12245-023-00485-1Impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno-arterial extracorporeal membrane oxygenationRyosuke Shimai0Shohei Ouchi1Tetsuro Miyazaki2Koji Hirabayashi3Hiroshi Abe4Kosuke Yabe5Midori Kakihara6Masaaki Maki7Hiroyuki Isogai8Takeshi Wada9Dai Ozaki10Yuki Yasuda11Fuminori Odagiri12Kazuhisa Takamura13Kenji Yaginuma14Ken Yokoyama15Takashi Tokano16Tohru Minamino17Department of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo Tokyo Koto Geriatric Medical CenterDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiology, Juntendo University Urayasu HospitalDepartment of Cardiovascular Biology and Medicine, Graduate School of Medicine, Juntendo UniversityAbstract Background Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) requires a large amount of economic and human resources. The presence of bystander cardiopulmonary resuscitation (CPR) was focused on selecting appropriate V-A ECMO candidates. Result This study retrospectively enrolled 39 patients with V-A ECMO due to out-of-hospital cardiac arrest (CA) between January 2010 and March 2019. The introduction criteria of V-A ECMO included the following: (1) < 75 years old, (2) CA on arrival, (3) < 40 min from CA to hospital arrival, (4) shockable rhythm, and (5) good activity of daily living (ADL). The prescribed introduction criteria were not met by 14 patients, but they were introduced to V-A ECMO at the discretion of their attending physicians and were also included in the analysis. Neurological prognosis at discharge was defined using The Glasgow-Pittsburgh Cerebral Performance and Overall Performance Categories of Brain Function (CPC). Patients were divided into good or poor neurological prognosis (CPC ≤ 2 or ≥ 3) groups (8 vs. 31 patients). The good prognosis group had a significantly larger number of patients who received bystander CPR (p = 0.04). The mean CPC at discharge was compared based on the combination with the presence of bystander CPR and all five original criteria. Patients who received bystander CPR and met all original five criteria showed significantly better CPC than patients who did not receive bystander CPR and did not meet some of the original five criteria (p = 0.046). Conclusion Considering the presence of bystander CPR help in selecting the appropriate candidate of V-A ECMO among out-of-hospital CA cases.https://doi.org/10.1186/s12245-023-00485-1Emergency cardiovascular care, Out-of-hospital cardiac arrestThe Glasgow-Pittsburgh Cerebral Performance and Overall Performance Categories of Brain FunctionIntensive care |
| spellingShingle | Ryosuke Shimai Shohei Ouchi Tetsuro Miyazaki Koji Hirabayashi Hiroshi Abe Kosuke Yabe Midori Kakihara Masaaki Maki Hiroyuki Isogai Takeshi Wada Dai Ozaki Yuki Yasuda Fuminori Odagiri Kazuhisa Takamura Kenji Yaginuma Ken Yokoyama Takashi Tokano Tohru Minamino Impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno-arterial extracorporeal membrane oxygenation International Journal of Emergency Medicine Emergency cardiovascular care, Out-of-hospital cardiac arrest The Glasgow-Pittsburgh Cerebral Performance and Overall Performance Categories of Brain Function Intensive care |
| title | Impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno-arterial extracorporeal membrane oxygenation |
| title_full | Impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno-arterial extracorporeal membrane oxygenation |
| title_fullStr | Impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno-arterial extracorporeal membrane oxygenation |
| title_full_unstemmed | Impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno-arterial extracorporeal membrane oxygenation |
| title_short | Impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno-arterial extracorporeal membrane oxygenation |
| title_sort | impact of bystander cardiopulmonary resuscitation on neurological outcomes in patients undergoing veno arterial extracorporeal membrane oxygenation |
| topic | Emergency cardiovascular care, Out-of-hospital cardiac arrest The Glasgow-Pittsburgh Cerebral Performance and Overall Performance Categories of Brain Function Intensive care |
| url | https://doi.org/10.1186/s12245-023-00485-1 |
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