An Update on Sexual Transmission of Zika Virus

Zika virus (ZIKV) is a single-stranded RNA virus belonging to the arthropod-borne flaviviruses (arboviruses) which are mainly transmitted by blood-sucking mosquitoes of the genus Aedes. ZIKV infection has been known to be rather asymptomatic or presented as febrile self-limited disease; however, dur...

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Main Authors: Hercules Sakkas, Petros Bozidis, Xenofon Giannakopoulos, Nikolaos Sofikitis, Chrissanthy Papadopoulou
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/7/3/66
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author Hercules Sakkas
Petros Bozidis
Xenofon Giannakopoulos
Nikolaos Sofikitis
Chrissanthy Papadopoulou
author_facet Hercules Sakkas
Petros Bozidis
Xenofon Giannakopoulos
Nikolaos Sofikitis
Chrissanthy Papadopoulou
author_sort Hercules Sakkas
collection DOAJ
description Zika virus (ZIKV) is a single-stranded RNA virus belonging to the arthropod-borne flaviviruses (arboviruses) which are mainly transmitted by blood-sucking mosquitoes of the genus Aedes. ZIKV infection has been known to be rather asymptomatic or presented as febrile self-limited disease; however, during the last decade the manifestation of ZIKV infection has been associated with a variety of neuroimmunological disorders including Guillain–Barré syndrome, microcephaly and other central nervous system abnormalities. More recently, there is accumulating evidence about sexual transmission of ZIKV, a trait that has never been observed in any other mosquito-borne flavivirus before. This article reviews the latest information regarding the latter and emerging role of ZIKV, focusing on the consequences of ZIKV infection on the male reproductive system and the epidemiology of human-to-human sexual transmission.
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spelling doaj.art-759d2b3b89e14bf6a2bcd4c3b291aa862022-12-22T03:59:09ZengMDPI AGPathogens2076-08172018-08-01736610.3390/pathogens7030066pathogens7030066An Update on Sexual Transmission of Zika VirusHercules Sakkas0Petros Bozidis1Xenofon Giannakopoulos2Nikolaos Sofikitis3Chrissanthy Papadopoulou4Microbiology Department, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, GreeceMicrobiology Department, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, GreeceDepartment of Urology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, GreeceDepartment of Urology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, GreeceMicrobiology Department, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, GreeceZika virus (ZIKV) is a single-stranded RNA virus belonging to the arthropod-borne flaviviruses (arboviruses) which are mainly transmitted by blood-sucking mosquitoes of the genus Aedes. ZIKV infection has been known to be rather asymptomatic or presented as febrile self-limited disease; however, during the last decade the manifestation of ZIKV infection has been associated with a variety of neuroimmunological disorders including Guillain–Barré syndrome, microcephaly and other central nervous system abnormalities. More recently, there is accumulating evidence about sexual transmission of ZIKV, a trait that has never been observed in any other mosquito-borne flavivirus before. This article reviews the latest information regarding the latter and emerging role of ZIKV, focusing on the consequences of ZIKV infection on the male reproductive system and the epidemiology of human-to-human sexual transmission.http://www.mdpi.com/2076-0817/7/3/66Zika virusflavivirusAedesHost-virus interactionstestissexual transmissionepidemics
spellingShingle Hercules Sakkas
Petros Bozidis
Xenofon Giannakopoulos
Nikolaos Sofikitis
Chrissanthy Papadopoulou
An Update on Sexual Transmission of Zika Virus
Pathogens
Zika virus
flavivirus
Aedes
Host-virus interactions
testis
sexual transmission
epidemics
title An Update on Sexual Transmission of Zika Virus
title_full An Update on Sexual Transmission of Zika Virus
title_fullStr An Update on Sexual Transmission of Zika Virus
title_full_unstemmed An Update on Sexual Transmission of Zika Virus
title_short An Update on Sexual Transmission of Zika Virus
title_sort update on sexual transmission of zika virus
topic Zika virus
flavivirus
Aedes
Host-virus interactions
testis
sexual transmission
epidemics
url http://www.mdpi.com/2076-0817/7/3/66
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