Initial TK-deficient HSV-1 infection in the lip alters contralateral lip challenge immune dynamics
Abstract Primary infection with herpes simplex type 1 (HSV-1) occurring around the mouth and nose switches rapidly to lifelong latent infection in sensitive trigeminal ganglia (TG) neurons. Sporadic reactivation of these latent reservoirs later in life is the cause of acute infections of the corneal...
Main Authors: | Antoine Rousseau, Oscar Haigh, Roger Legrand, Jean-Louis Palgen, Julien Lemaitre, Claire Deback, Noémie Oziol, Patrick Lomonte, Marc Labetoulle |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-12597-4 |
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