Simultaneous late-gadolinium enhancement and T1 mapping of fibrosis and a novel cell-based combination therapy in hypertensive mice

Simultaneous late-gadolinium enhancement and T1 mapping of fibrosis and a novel cell-based combination therapy in hypertensive mice

Fibrosis is a hallmark of chronic hypertension and disrupts the viability of human bone marrow-derived mesenchymal stromal cells (BM-MSCs) post-transplantation. This study thus, determined whether the anti-fibrotic drug, serelaxin (RLX), could enhance the therapeutic effects of BM-MSCs or BM-MSC-der...

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Bibliographic Details
Main Authors: Yifang Li, Gang Zheng, Ekaterina Salimova, Brad R.S. Broughton, Sharon D. Ricardo, Michael de Veer, Chrishan S. Samuel
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Hypertension
Cardiorenal syndrome
Fibrosis
Cardiac MRI
Relaxin
Bone marrow-MSCs
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222014585

Internet

http://www.sciencedirect.com/science/article/pii/S0753332222014585

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