The influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes: a retrospective study
Abstract Background Percutaneous transhepatic gallbladder drainage (PTGBD) is recommended for acute cholecystitis patients at high risk for surgical treatment. However, there is no evidence about the best timing of surgery after PTGBD. Here, we retrospectively investigated the influence of the inter...
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| Language: | English |
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BMC
2021-05-01
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| Series: | BMC Gastroenterology |
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| Online Access: | https://doi.org/10.1186/s12876-021-01810-9 |
| _version_ | 1818939721751986176 |
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| author | Koichi Kimura Eisuke Adachi Sachie Omori Ayako Toyohara Takahiro Higashi Kippei Ohgaki Shuhei Ito Shin-ichiro Maehara Toshihiko Nakamura Yoichi Ikeda Yoshihiko Maehara |
| author_facet | Koichi Kimura Eisuke Adachi Sachie Omori Ayako Toyohara Takahiro Higashi Kippei Ohgaki Shuhei Ito Shin-ichiro Maehara Toshihiko Nakamura Yoichi Ikeda Yoshihiko Maehara |
| author_sort | Koichi Kimura |
| collection | DOAJ |
| description | Abstract Background Percutaneous transhepatic gallbladder drainage (PTGBD) is recommended for acute cholecystitis patients at high risk for surgical treatment. However, there is no evidence about the best timing of surgery after PTGBD. Here, we retrospectively investigated the influence of the interval between PTGBD and surgery on perioperative outcomes and examined the optimal timing of surgery after PTGBD. Methods We performed a retrospective analysis of 22 patients who underwent cholecystectomy after PTGBD from January 2008 to August 2019. We examined perioperative factors between patients with an interval of ≤ 7 days between PTGBD and cholecystectomy (≤ 7-day group; n = 12) and those with an interval of ≥ 8 days (≥ 8-day group; n = 10). Moreover, we also examined perioperative factors between patients with an interval of ≤ 14 days from PTGBD to cholecystectomy (≤ 14-day group; n = 10) and those with an interval of ≥ 15 days (≥ 15-day group; n = 12). Results Of the 22 patients, 9 had Grade I cholecystitis, 12 had Grade II cholecystitis, and 2 had Grade III cholecystitis. Nine patients had high-grade cholecystitis before PTGBD and 13 had a poor general condition. We examined perioperative factors between patients with an interval of ≤ 7 days between PTGBD and cholecystectomy (≤ 7-day group; n = 12) and those with an interval of ≥ 8 days (≥ 8-day group; n = 10). The C-reactive protein (CRP) level before surgery was significantly higher (12.70 ± 1.95 mg/dL vs. 1.13 ± 2.13 mg/dL, p = 0.0007) and the total hospitalization was shorter (17.6 ± 8.0 days vs. 54.1 ± 8.8 days, p = 0.0060) in the ≤ 7-day group than in the ≥ 8-day group. We also examined perioperative factors between patients with an interval of ≤ 14 days from PTGBD to cholecystectomy (≤ 14-day group; n = 14) and those with an interval of ≥ 15 days (≥ 15-day group; n = 8). The CRP level before surgery was significantly higher (11.13 ± 2.00 mg/dL vs. 0.99 ± 2.64 mg/dL, p = 0.0062) and the total hospitalization was shorter (19.5 ± 7.2 days vs. 59.9 ± 9.5 days, p = 0.0029) in the ≤ 14-day group than in the ≥ 15-day group. However, there were no significant differences between the ≤ 14-day group and the ≥ 15-day group in the levels of hepatic enzymes before surgery, adhesion grade, amount of bleeding during surgery, operative duration, frequency of surgical complications, or length of hospitalization after surgery. Conclusions The interval between PTGBD and surgery has little influence on perioperative outcomes. |
| first_indexed | 2024-12-20T06:28:15Z |
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| id | doaj.art-75a0da237de04ed3831a16be66d02821 |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-12-20T06:28:15Z |
| publishDate | 2021-05-01 |
| publisher | BMC |
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| series | BMC Gastroenterology |
| spelling | doaj.art-75a0da237de04ed3831a16be66d028212022-12-21T19:50:13ZengBMCBMC Gastroenterology1471-230X2021-05-012111710.1186/s12876-021-01810-9The influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes: a retrospective studyKoichi Kimura0Eisuke Adachi1Sachie Omori2Ayako Toyohara3Takahiro Higashi4Kippei Ohgaki5Shuhei Ito6Shin-ichiro Maehara7Toshihiko Nakamura8Yoichi Ikeda9Yoshihiko Maehara10Department of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersDepartment of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School TeachersAbstract Background Percutaneous transhepatic gallbladder drainage (PTGBD) is recommended for acute cholecystitis patients at high risk for surgical treatment. However, there is no evidence about the best timing of surgery after PTGBD. Here, we retrospectively investigated the influence of the interval between PTGBD and surgery on perioperative outcomes and examined the optimal timing of surgery after PTGBD. Methods We performed a retrospective analysis of 22 patients who underwent cholecystectomy after PTGBD from January 2008 to August 2019. We examined perioperative factors between patients with an interval of ≤ 7 days between PTGBD and cholecystectomy (≤ 7-day group; n = 12) and those with an interval of ≥ 8 days (≥ 8-day group; n = 10). Moreover, we also examined perioperative factors between patients with an interval of ≤ 14 days from PTGBD to cholecystectomy (≤ 14-day group; n = 10) and those with an interval of ≥ 15 days (≥ 15-day group; n = 12). Results Of the 22 patients, 9 had Grade I cholecystitis, 12 had Grade II cholecystitis, and 2 had Grade III cholecystitis. Nine patients had high-grade cholecystitis before PTGBD and 13 had a poor general condition. We examined perioperative factors between patients with an interval of ≤ 7 days between PTGBD and cholecystectomy (≤ 7-day group; n = 12) and those with an interval of ≥ 8 days (≥ 8-day group; n = 10). The C-reactive protein (CRP) level before surgery was significantly higher (12.70 ± 1.95 mg/dL vs. 1.13 ± 2.13 mg/dL, p = 0.0007) and the total hospitalization was shorter (17.6 ± 8.0 days vs. 54.1 ± 8.8 days, p = 0.0060) in the ≤ 7-day group than in the ≥ 8-day group. We also examined perioperative factors between patients with an interval of ≤ 14 days from PTGBD to cholecystectomy (≤ 14-day group; n = 14) and those with an interval of ≥ 15 days (≥ 15-day group; n = 8). The CRP level before surgery was significantly higher (11.13 ± 2.00 mg/dL vs. 0.99 ± 2.64 mg/dL, p = 0.0062) and the total hospitalization was shorter (19.5 ± 7.2 days vs. 59.9 ± 9.5 days, p = 0.0029) in the ≤ 14-day group than in the ≥ 15-day group. However, there were no significant differences between the ≤ 14-day group and the ≥ 15-day group in the levels of hepatic enzymes before surgery, adhesion grade, amount of bleeding during surgery, operative duration, frequency of surgical complications, or length of hospitalization after surgery. Conclusions The interval between PTGBD and surgery has little influence on perioperative outcomes.https://doi.org/10.1186/s12876-021-01810-9Acute cholecystitisPTGBDCholecystectomy |
| spellingShingle | Koichi Kimura Eisuke Adachi Sachie Omori Ayako Toyohara Takahiro Higashi Kippei Ohgaki Shuhei Ito Shin-ichiro Maehara Toshihiko Nakamura Yoichi Ikeda Yoshihiko Maehara The influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes: a retrospective study BMC Gastroenterology Acute cholecystitis PTGBD Cholecystectomy |
| title | The influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes: a retrospective study |
| title_full | The influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes: a retrospective study |
| title_fullStr | The influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes: a retrospective study |
| title_full_unstemmed | The influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes: a retrospective study |
| title_short | The influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes: a retrospective study |
| title_sort | influence of the interval between percutaneous transhepatic gallbladder drainage and cholecystectomy on perioperative outcomes a retrospective study |
| topic | Acute cholecystitis PTGBD Cholecystectomy |
| url | https://doi.org/10.1186/s12876-021-01810-9 |
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