MxB inhibits long interspersed element type 1 retrotransposition.

MxB inhibits long interspersed element type 1 retrotransposition.

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Long interspersed element type 1 (LINE-1, also L1 for short) is the only autonomously transposable element in the human genome. Its insertion into a new genomic site may disrupt the function of genes, potentially causing genetic diseases. Cells have thus evolved a battery of mechanisms to tightly co...

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Bibliographic Details
Main Authors: Yu Huang, Fengwen Xu, Shan Mei, Xiaoman Liu, Fei Zhao, Liang Wei, Zhangling Fan, Yamei Hu, Liming Wang, Bin Ai, Shan Cen, Chen Liang, Fei Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010034

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