Development of a reversed-phase HPLC method for determination of related impurities of Lenalidomide

Development of a reversed-phase HPLC method for determination of related impurities of Lenalidomide

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In this project, we have developed a reversed phase liquid chromatography method for separation and determination of lenalidomide (LENA) and related substances by using C-8 (250×4.6 mm ID, 5 μm) HPCL column. The mobile phases A and B were phosphate buffer at Ph=3.30, and (methanol:acetonitrile)(1:5...

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Bibliographic Details
Main Authors: Seyyed Amir Siadati, Meghdad Payab, Abolghasem Beheshti
Format: Article
Language:English
Published: Iranian Chemical Science and Technologies Association 2020-04-01
Series:Chemical Review and Letters
Subjects:
lenalidomide
related substances
hplc
method development
uv detector
Online Access:http://www.chemrevlett.com/article_105647_7b9118b6d63191b5e1fc99037d18bd6e.pdf

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