Patterns of Thyroid Cancers in Southeastern Nigeria: A 15 Year Histopathologic Review (2000-2014)
Introduction: Thyroid Cancer (TC) continues to be the most common endocrine cancer with a worldwide increase in incidence over the last three decades. This trend has been reported in all continents except Africa, where detection is adjudged to be insufficient, making it imperative for us to re-e...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/10418/26971_CE(RA1)_F(T)_PF1(RB_GG)_PFA(RB_GG).pdf |
| Summary: | Introduction: Thyroid Cancer (TC) continues to be the most
common endocrine cancer with a worldwide increase in incidence
over the last three decades. This trend has been reported in all
continents except Africa, where detection is adjudged to be
insufficient, making it imperative for us to re-evaluate the patterns
in our environment.
Aim: To determine the patterns of TCs in Southeastern Nigeria.
Materials and Methods: This was a 15-year retrospective review
of all thyroidectomy specimens received at the Department of
Morbid Anatomy, University of Nigeria, Enugu Campus, Enugu,
Nigeria. The age, sex and histologic subtypes of diagnosed
TCs were analysed using Predictive Analytics Software (PASW)
Statistics for Windows, Version 18 (Chicago: SPSS Inc.) and the
results were expressed in descriptive statistics.
Results: Sixty one cases of TCs were identified in this study
constituting 10.8% of thyroid biopsies received at our centre
during the period under review. There were 51 (83.6%) females
and 10 (16.4%) males giving a ratio of 5.1:1, and a mean age
of 45.9 years. The commonest histologic type was Papillary
Thyroid Carcinoma (PTC) (42.6%), followed by; follicular
thyroid carcinoma (37.7%), medullary thyroid carcinoma
(4.9%), anaplastic carcinomas (3.3%), Non-Hodgkin lymphoma
(1.6%) and metastatic squamous cell carcinoma (3.3%). Mixed
papillary/ follicular carcinoma (4.9%) and mixed papillary/
anaplastic carcinoma (1.6%) were also identified.
Conclusion: TC continues to predominate amongst females,
occurring mainly in early middle age group in Southeastern
Nigeria. PTC is now the commonest histologic type. |
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| ISSN: | 2249-782X 0973-709X |