Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019
Abstract Background We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) and to investigate demographic factors and comorbidities associated with all-cause mortality by aggregating and utilizing large-scale administrative healthcare data from the Unified National Electron...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | BMC Endocrine Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12902-022-01200-6 |
| _version_ | 1811230613338849280 |
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| author | Dinara Galiyeva Arnur Gusmanov Yesbolat Sakko Alpamys Issanov Kuralay Atageldiyeva Kainar Kadyrzhanuly Aiymzhan Nurpeissova Marzhan Rakhimzhanova Aigul Durmanova Antonio Sarria-Santamera Abduzhappar Gaipov |
| author_facet | Dinara Galiyeva Arnur Gusmanov Yesbolat Sakko Alpamys Issanov Kuralay Atageldiyeva Kainar Kadyrzhanuly Aiymzhan Nurpeissova Marzhan Rakhimzhanova Aigul Durmanova Antonio Sarria-Santamera Abduzhappar Gaipov |
| author_sort | Dinara Galiyeva |
| collection | DOAJ |
| description | Abstract Background We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) and to investigate demographic factors and comorbidities associated with all-cause mortality by aggregating and utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) of Kazakhstan for 2014–2019 years period. Methods A total of 475,539 individuals were included in the analyses. The median years of follow-up for Type 1 DM patients accounted for 4.7 years and 4.5 years in Type 2 DM patients. We used Kaplan-Meier and log-rank test to calculate failure function and differences in survival by age, sex, ethnicity, and comorbidities with all-cause mortality for Type 1 and Type 2 DM. Cox proportional hazards regression analysis was used to obtain crude and adjusted hazard ratios. Results Prevalence of Type 1 and Type 2 DM increased 1.7 times from 2014 to 2019. Mortality of Type 1 and Type 2 DM also increased 4 times and 6 times from 2014 to 2019, respectively. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh in patients with Type 1 and Type 2 DM. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death. Conclusion The prevalence and mortality rate of Type 1 and Type 2 DM increased during the years 2014–2019 in Kazakhstan. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death. |
| first_indexed | 2024-04-12T10:31:36Z |
| format | Article |
| id | doaj.art-75a8ad1eef5f4d5ab35278fc1763888d |
| institution | Directory Open Access Journal |
| issn | 1472-6823 |
| language | English |
| last_indexed | 2024-04-12T10:31:36Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Endocrine Disorders |
| spelling | doaj.art-75a8ad1eef5f4d5ab35278fc1763888d2022-12-22T03:36:50ZengBMCBMC Endocrine Disorders1472-68232022-11-0122111010.1186/s12902-022-01200-6Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019Dinara Galiyeva0Arnur Gusmanov1Yesbolat Sakko2Alpamys Issanov3Kuralay Atageldiyeva4Kainar Kadyrzhanuly5Aiymzhan Nurpeissova6Marzhan Rakhimzhanova7Aigul Durmanova8Antonio Sarria-Santamera9Abduzhappar Gaipov10Department of Medicine, School of Medicine, Nazarbayev UniversityDepartment of Medicine, School of Medicine, Nazarbayev UniversityDepartment of Medicine, School of Medicine, Nazarbayev UniversityDepartment of Medicine, School of Medicine, Nazarbayev UniversityDepartment of Medicine, School of Medicine, Nazarbayev UniversityDepartment of Medicine, School of Medicine, Nazarbayev UniversityDepartment of Medical Information Analysis of Outpatient and Polyclinic Care, Republican Center of Electronic HealthcareClinical Academic Department of Pediatrics, University Medical CenterClinical Academic Department of Internal Medicine, University Medical CenterDepartment of Medicine, School of Medicine, Nazarbayev UniversityDepartment of Medicine, School of Medicine, Nazarbayev UniversityAbstract Background We aimed to explore descriptive epidemiology of T1 and T2 Diabetes Mellitus (DM) and to investigate demographic factors and comorbidities associated with all-cause mortality by aggregating and utilizing large-scale administrative healthcare data from the Unified National Electronic Health System (UNEHS) of Kazakhstan for 2014–2019 years period. Methods A total of 475,539 individuals were included in the analyses. The median years of follow-up for Type 1 DM patients accounted for 4.7 years and 4.5 years in Type 2 DM patients. We used Kaplan-Meier and log-rank test to calculate failure function and differences in survival by age, sex, ethnicity, and comorbidities with all-cause mortality for Type 1 and Type 2 DM. Cox proportional hazards regression analysis was used to obtain crude and adjusted hazard ratios. Results Prevalence of Type 1 and Type 2 DM increased 1.7 times from 2014 to 2019. Mortality of Type 1 and Type 2 DM also increased 4 times and 6 times from 2014 to 2019, respectively. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh in patients with Type 1 and Type 2 DM. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death. Conclusion The prevalence and mortality rate of Type 1 and Type 2 DM increased during the years 2014–2019 in Kazakhstan. Male sex, older age and Kazakh ethnicity were associated with a higher risk of all-cause death compared to females, younger age and other nationalities than Kazakh. Coronary artery disease, diabetic nephropathy, stroke, amputations and neoplasms were associated with a higher risk of all-cause death.https://doi.org/10.1186/s12902-022-01200-6DiabetesSurvivalMortalityEpidemiologyComorbidities |
| spellingShingle | Dinara Galiyeva Arnur Gusmanov Yesbolat Sakko Alpamys Issanov Kuralay Atageldiyeva Kainar Kadyrzhanuly Aiymzhan Nurpeissova Marzhan Rakhimzhanova Aigul Durmanova Antonio Sarria-Santamera Abduzhappar Gaipov Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019 BMC Endocrine Disorders Diabetes Survival Mortality Epidemiology Comorbidities |
| title | Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019 |
| title_full | Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019 |
| title_fullStr | Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019 |
| title_full_unstemmed | Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019 |
| title_short | Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019 |
| title_sort | epidemiology of type 1 and type 2 diabetes mellitus in kazakhstan data from unified national electronic health system 2014 2019 |
| topic | Diabetes Survival Mortality Epidemiology Comorbidities |
| url | https://doi.org/10.1186/s12902-022-01200-6 |
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