Hormonal regulation of telomerase activity and hTERT expression in steroid-regulated tissues and cancer

Hormonal regulation of telomerase activity and hTERT expression in steroid-regulated tissues and cancer

Abstract Naturally, in somatic cells chromosome ends (telomeres) shorten during each cell division. This process ensures to limit proliferation of somatic cells to avoid malignant proliferation; however, it leads to proliferative senescence. Telomerase contains the reverse transcriptase TERT, which...

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Bibliographic Details
Main Authors: Mohammad Taheri, Soudeh Ghafouri-Fard, Sajad Najafi, Julia Kallenbach, Elmira Keramatfar, Golnaz Atri Roozbahani, Mehdi Heidari Horestani, Bashdar Mahmud Hussen, Aria Baniahmad
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Cancer Cell International
Subjects:
Telomerase
Hormone
Growth factor
Prostate cancer
Breast cancer
Online Access:https://doi.org/10.1186/s12935-022-02678-9

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