10 Pre-clinical studies of sotagliflozin in hypertrophic cardiomyopathy

OBJECTIVES/GOALS: Study the regulatory role of sodium glucose co-transporter 1 (SGLT1) in cardiomyocytes and the therapeutic potential of sotagliflozin in hypertrophic cardiomyopathy (HCM) by (a) quantifying SGLT1 expression in HCM and (b) examining the impact of sotagliflozin on cardiac mechanics....

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Rebecca Taichman, Benjamin Lee, Kenneth Margulies, Sharlene Day
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Cambridge University Press 2024-04-01
Σειρά:Journal of Clinical and Translational Science
Διαθέσιμο Online:https://www.cambridge.org/core/product/identifier/S2059866124000311/type/journal_article