10 Pre-clinical studies of sotagliflozin in hypertrophic cardiomyopathy

OBJECTIVES/GOALS: Study the regulatory role of sodium glucose co-transporter 1 (SGLT1) in cardiomyocytes and the therapeutic potential of sotagliflozin in hypertrophic cardiomyopathy (HCM) by (a) quantifying SGLT1 expression in HCM and (b) examining the impact of sotagliflozin on cardiac mechanics....

Descrición completa

Detalles Bibliográficos
Main Authors: Rebecca Taichman, Benjamin Lee, Kenneth Margulies, Sharlene Day
Formato: Artigo
Idioma:English
Publicado: Cambridge University Press 2024-04-01
Series:Journal of Clinical and Translational Science
Acceso en liña:https://www.cambridge.org/core/product/identifier/S2059866124000311/type/journal_article