10 Pre-clinical studies of sotagliflozin in hypertrophic cardiomyopathy

OBJECTIVES/GOALS: Study the regulatory role of sodium glucose co-transporter 1 (SGLT1) in cardiomyocytes and the therapeutic potential of sotagliflozin in hypertrophic cardiomyopathy (HCM) by (a) quantifying SGLT1 expression in HCM and (b) examining the impact of sotagliflozin on cardiac mechanics....

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Rebecca Taichman, Benjamin Lee, Kenneth Margulies, Sharlene Day
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Cambridge University Press 2024-04-01
Цуврал:Journal of Clinical and Translational Science
Онлайн хандалт:https://www.cambridge.org/core/product/identifier/S2059866124000311/type/journal_article