Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury
In this article, we review how acupuncture regulates oxidative stress to prevent ischemia−reperfusion injury. We electronically searched databases, including PubMed, Clinical Key and the Cochrane Library, from their inception to November 2019 by using the following medical subject headings...
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-03-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/9/3/248 |
| _version_ | 1797706119750090752 |
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| author | Chao-Hsien Chen Ching-Liang Hsieh |
| author_facet | Chao-Hsien Chen Ching-Liang Hsieh |
| author_sort | Chao-Hsien Chen |
| collection | DOAJ |
| description | In this article, we review how acupuncture regulates oxidative stress to prevent ischemia−reperfusion injury. We electronically searched databases, including PubMed, Clinical Key and the Cochrane Library, from their inception to November 2019 by using the following medical subject headings and keywords: acupuncture, ischemia-reperfusion injury, oxidative stress, reactive oxygen species, and antioxidants. We concluded that acupuncture is effective in treating oxidation after ischemia-reperfusion injury. In addition to increasing the activity of antioxidant enzymes and downregulating the generation of reactive oxygen species (ROS), acupuncture also repairs the DNA, lipids, and proteins attacked by ROS and mediates downstream of the ROS pathway to apoptosis. |
| first_indexed | 2024-03-12T05:47:34Z |
| format | Article |
| id | doaj.art-75b127b30c814961aed8899ee8cf155e |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-12T05:47:34Z |
| publishDate | 2020-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-75b127b30c814961aed8899ee8cf155e2023-09-03T05:30:49ZengMDPI AGAntioxidants2076-39212020-03-019324810.3390/antiox9030248antiox9030248Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion InjuryChao-Hsien Chen0Ching-Liang Hsieh1Department of Chinese Medicine, China Medical University Hospital, Taichung 40447, TaiwanDepartment of Chinese Medicine, China Medical University Hospital, Taichung 40447, TaiwanIn this article, we review how acupuncture regulates oxidative stress to prevent ischemia−reperfusion injury. We electronically searched databases, including PubMed, Clinical Key and the Cochrane Library, from their inception to November 2019 by using the following medical subject headings and keywords: acupuncture, ischemia-reperfusion injury, oxidative stress, reactive oxygen species, and antioxidants. We concluded that acupuncture is effective in treating oxidation after ischemia-reperfusion injury. In addition to increasing the activity of antioxidant enzymes and downregulating the generation of reactive oxygen species (ROS), acupuncture also repairs the DNA, lipids, and proteins attacked by ROS and mediates downstream of the ROS pathway to apoptosis.https://www.mdpi.com/2076-3921/9/3/248acupunctureoxygen free radicalischemia-reperfusion injury |
| spellingShingle | Chao-Hsien Chen Ching-Liang Hsieh Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury Antioxidants acupuncture oxygen free radical ischemia-reperfusion injury |
| title | Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury |
| title_full | Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury |
| title_fullStr | Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury |
| title_full_unstemmed | Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury |
| title_short | Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury |
| title_sort | effect of acupuncture on oxidative stress induced by cerebral ischemia reperfusion injury |
| topic | acupuncture oxygen free radical ischemia-reperfusion injury |
| url | https://www.mdpi.com/2076-3921/9/3/248 |
| work_keys_str_mv | AT chaohsienchen effectofacupunctureonoxidativestressinducedbycerebralischemiareperfusioninjury AT chinglianghsieh effectofacupunctureonoxidativestressinducedbycerebralischemiareperfusioninjury |