Antineutrophil cytoplasmic autoantibodies in uveitis

Antineutrophil cytoplasmic autoantibodies were detected in patients with some autoimmune and vascular disease such as Wegner’s granulomatosis polyarthritis nodosa and systemic lupus erythematosus. Indirect immunofluorescence technique was employed to detect these autoantibodies. By this method, two...

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Main Authors: "Vodjgani M, Baghbani HN, Hajati J "
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2000-12-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/2316
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author "Vodjgani M
Baghbani HN
Hajati J "
author_facet "Vodjgani M
Baghbani HN
Hajati J "
author_sort "Vodjgani M
collection DOAJ
description Antineutrophil cytoplasmic autoantibodies were detected in patients with some autoimmune and vascular disease such as Wegner’s granulomatosis polyarthritis nodosa and systemic lupus erythematosus. Indirect immunofluorescence technique was employed to detect these autoantibodies. By this method, two general patterns of antineutrophil cytoplasmic autoantibodies were seen: a cytoplasmic (C-ANCA) and a perinuclear form (P-ANCA). These antibodies also were observed in uveitis. In this study the presence of antineutrophil cytoplasmic autoantibodies in 25 patients with uveitis and its relationship with uveitis and its relationship with anatomical location of the disease is evaluated. According to the results antineutrophil cytoplasmic autoantibodies was detected in 16% (4 out of 25) of the patients all of them being C-ANCA type. The results also showed that there was not any significant correlation between the presence of antineutrophil cytoplasmic autoantibodies and anatomical location of the disease (P=0.65).
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spelling doaj.art-75b5165835724ccebb7a2b3bbabba6212022-12-21T18:12:54ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942000-12-01384Antineutrophil cytoplasmic autoantibodies in uveitis "Vodjgani M0 Baghbani HN1 Hajati J "2 Antineutrophil cytoplasmic autoantibodies were detected in patients with some autoimmune and vascular disease such as Wegner’s granulomatosis polyarthritis nodosa and systemic lupus erythematosus. Indirect immunofluorescence technique was employed to detect these autoantibodies. By this method, two general patterns of antineutrophil cytoplasmic autoantibodies were seen: a cytoplasmic (C-ANCA) and a perinuclear form (P-ANCA). These antibodies also were observed in uveitis. In this study the presence of antineutrophil cytoplasmic autoantibodies in 25 patients with uveitis and its relationship with uveitis and its relationship with anatomical location of the disease is evaluated. According to the results antineutrophil cytoplasmic autoantibodies was detected in 16% (4 out of 25) of the patients all of them being C-ANCA type. The results also showed that there was not any significant correlation between the presence of antineutrophil cytoplasmic autoantibodies and anatomical location of the disease (P=0.65).https://acta.tums.ac.ir/index.php/acta/article/view/2316Antineutrophil cytoplasmic autoantibodiesUveitis
spellingShingle "Vodjgani M
Baghbani HN
Hajati J "
Antineutrophil cytoplasmic autoantibodies in uveitis
Acta Medica Iranica
Antineutrophil cytoplasmic autoantibodies
Uveitis
title Antineutrophil cytoplasmic autoantibodies in uveitis
title_full Antineutrophil cytoplasmic autoantibodies in uveitis
title_fullStr Antineutrophil cytoplasmic autoantibodies in uveitis
title_full_unstemmed Antineutrophil cytoplasmic autoantibodies in uveitis
title_short Antineutrophil cytoplasmic autoantibodies in uveitis
title_sort antineutrophil cytoplasmic autoantibodies in uveitis
topic Antineutrophil cytoplasmic autoantibodies
Uveitis
url https://acta.tums.ac.ir/index.php/acta/article/view/2316
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AT baghbanihn antineutrophilcytoplasmicautoantibodiesinuveitis
AT hajatij antineutrophilcytoplasmicautoantibodiesinuveitis