Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications.
BACKGROUND:Various stimuli can trigger migraines in susceptible individuals. We examined migraine trigger factors by using a smartphone headache diary application. METHOD:Episodic migraineurs who agreed to participate in our study downloaded smartphone headache diary application, which was designed...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4764678?pdf=render |
| _version_ | 1818059550307123200 |
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| author | Jeong-Wook Park Min Kyung Chu Jae-Moon Kim Sang-Gue Park Soo-Jin Cho |
| author_facet | Jeong-Wook Park Min Kyung Chu Jae-Moon Kim Sang-Gue Park Soo-Jin Cho |
| author_sort | Jeong-Wook Park |
| collection | DOAJ |
| description | BACKGROUND:Various stimuli can trigger migraines in susceptible individuals. We examined migraine trigger factors by using a smartphone headache diary application. METHOD:Episodic migraineurs who agreed to participate in our study downloaded smartphone headache diary application, which was designed to capture the details regarding headache trigger factors and characteristics for 3 months. The participants were asked to access the smartphone headache diary application daily and to confirm the presence of a headache and input the types of trigger factors. RESULTS:Sixty-two participants kept diary entries until the end of the study. The diary data for 4,579 days were analyzed. In this data set, 1,099 headache days (336 migraines, 763 non-migraine headaches) were recorded; of these, 772 headache events had with trigger factors, and 327 events did not have trigger factors. The common trigger factors that were present on headache days included stress, fatigue, sleep deprivation, hormonal changes, and weather changes. The likelihood of a headache trigger was 57.7% for stress, 55.1% for sleep deprivation, 48.5% for fatigue, and 46.5% for any trigger. The headaches with trigger factors were associated with greater pain intensity (p<0.001), headache-related disability (p<0.001), abortive medication use (p = 0.02), and the proportion of migraine (p < 0.001), relative to those without trigger factors. Traveling (odd ratios [OR]: 6.4), hormonal changes (OR: 3.5), noise (OR: 2.8), alcohol (OR: 2.5), overeating (OR: 2.4), and stress (OR:1.8) were significantly associated with migraines compared to non-migraine headaches. The headaches that were associated with hormonal changes or noise were more often migraines, regardless of the preventive medication. The headaches due to stress, overeating, alcohol, and traveling were more often migraines without preventive medication, but it was not evident with preventive medication. CONCLUSION:Smartphone headache diary application is an effective tool to assess migraine trigger factors. The headaches with trigger factors had greater severity or migraine features. The type of triggers and the presence of preventive medication influenced the headache characteristics; hence, an investigation of trigger factors would be helpful in understanding migraine occurrences. |
| first_indexed | 2024-12-10T13:18:18Z |
| format | Article |
| id | doaj.art-75b6741da3514d31b48c2e2c1eb49e43 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-10T13:18:18Z |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-75b6741da3514d31b48c2e2c1eb49e432022-12-22T01:47:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01112e014957710.1371/journal.pone.0149577Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications.Jeong-Wook ParkMin Kyung ChuJae-Moon KimSang-Gue ParkSoo-Jin ChoBACKGROUND:Various stimuli can trigger migraines in susceptible individuals. We examined migraine trigger factors by using a smartphone headache diary application. METHOD:Episodic migraineurs who agreed to participate in our study downloaded smartphone headache diary application, which was designed to capture the details regarding headache trigger factors and characteristics for 3 months. The participants were asked to access the smartphone headache diary application daily and to confirm the presence of a headache and input the types of trigger factors. RESULTS:Sixty-two participants kept diary entries until the end of the study. The diary data for 4,579 days were analyzed. In this data set, 1,099 headache days (336 migraines, 763 non-migraine headaches) were recorded; of these, 772 headache events had with trigger factors, and 327 events did not have trigger factors. The common trigger factors that were present on headache days included stress, fatigue, sleep deprivation, hormonal changes, and weather changes. The likelihood of a headache trigger was 57.7% for stress, 55.1% for sleep deprivation, 48.5% for fatigue, and 46.5% for any trigger. The headaches with trigger factors were associated with greater pain intensity (p<0.001), headache-related disability (p<0.001), abortive medication use (p = 0.02), and the proportion of migraine (p < 0.001), relative to those without trigger factors. Traveling (odd ratios [OR]: 6.4), hormonal changes (OR: 3.5), noise (OR: 2.8), alcohol (OR: 2.5), overeating (OR: 2.4), and stress (OR:1.8) were significantly associated with migraines compared to non-migraine headaches. The headaches that were associated with hormonal changes or noise were more often migraines, regardless of the preventive medication. The headaches due to stress, overeating, alcohol, and traveling were more often migraines without preventive medication, but it was not evident with preventive medication. CONCLUSION:Smartphone headache diary application is an effective tool to assess migraine trigger factors. The headaches with trigger factors had greater severity or migraine features. The type of triggers and the presence of preventive medication influenced the headache characteristics; hence, an investigation of trigger factors would be helpful in understanding migraine occurrences.http://europepmc.org/articles/PMC4764678?pdf=render |
| spellingShingle | Jeong-Wook Park Min Kyung Chu Jae-Moon Kim Sang-Gue Park Soo-Jin Cho Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications. PLoS ONE |
| title | Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications. |
| title_full | Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications. |
| title_fullStr | Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications. |
| title_full_unstemmed | Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications. |
| title_short | Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications. |
| title_sort | analysis of trigger factors in episodic migraineurs using a smartphone headache diary applications |
| url | http://europepmc.org/articles/PMC4764678?pdf=render |
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