Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry
Dehydrated vegetables are popular in instant foods, but few reports have focused on their pesticide residues. This research developed and validated a modified QuEChERS method combined with ultra-performance liquid chromatography–tandem mass spectrometry to determine 19 kinds of neonicotinoid and car...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/12/4/699 |
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| author | Bingxin Yang Sheng Wang Wen Ma Guanlin Li Mengling Tu Zhiyong Ma Qinghe Zhang Hongmei Li Xianjiang Li |
| author_facet | Bingxin Yang Sheng Wang Wen Ma Guanlin Li Mengling Tu Zhiyong Ma Qinghe Zhang Hongmei Li Xianjiang Li |
| author_sort | Bingxin Yang |
| collection | DOAJ |
| description | Dehydrated vegetables are popular in instant foods, but few reports have focused on their pesticide residues. This research developed and validated a modified QuEChERS method combined with ultra-performance liquid chromatography–tandem mass spectrometry to determine 19 kinds of neonicotinoid and carbamate pesticides in freeze-dried cabbage. Herein, acetonitrile/water (<i>v/v</i> = 2:1) was selected in the extraction step. Meanwhile, 4 g anhydrous magnesium sulfate and 1 g sodium chloride were applied to the partitioning step. Dispersive solid-phase extraction sorbents were selected, and liquid chromatography conditions were further optimized for dealing with the matrix effect. The limits of quantification ranged from 1.0 to 10.0 μg/kg. The validation results were acceptable, with average recoveries of 78.7–114.0% and relative standard deviations below 14.2%. The method recoveries were closely related to the volume proportion of water in the extractant. Finally, the developed method was applied to real freeze-dried cabbages and four pesticides (propamocarb, imidacloprid, acetamiprid, and thiacloprid) were detected in six samples. |
| first_indexed | 2024-03-11T08:49:55Z |
| format | Article |
| id | doaj.art-75b7b3431fc54746a0408216132ff486 |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-11T08:49:55Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-75b7b3431fc54746a0408216132ff4862023-11-16T20:29:19ZengMDPI AGFoods2304-81582023-02-0112469910.3390/foods12040699Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography–Tandem Mass SpectrometryBingxin Yang0Sheng Wang1Wen Ma2Guanlin Li3Mengling Tu4Zhiyong Ma5Qinghe Zhang6Hongmei Li7Xianjiang Li8Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, ChinaKey Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, ChinaState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, ChinaCollege of Plant Protection, Shandong Agricultural University, Tai’an 271018, ChinaKey Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, ChinaBeijing Advanced Innovation Center for Soft Matter Science and Engineering, State Key Laboratory of Organic-Inorganic Composites, College of Chemical Engineering, Beijing University of Chemical Technology, Beijing 10029, ChinaKey Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, ChinaKey Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, ChinaKey Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, ChinaDehydrated vegetables are popular in instant foods, but few reports have focused on their pesticide residues. This research developed and validated a modified QuEChERS method combined with ultra-performance liquid chromatography–tandem mass spectrometry to determine 19 kinds of neonicotinoid and carbamate pesticides in freeze-dried cabbage. Herein, acetonitrile/water (<i>v/v</i> = 2:1) was selected in the extraction step. Meanwhile, 4 g anhydrous magnesium sulfate and 1 g sodium chloride were applied to the partitioning step. Dispersive solid-phase extraction sorbents were selected, and liquid chromatography conditions were further optimized for dealing with the matrix effect. The limits of quantification ranged from 1.0 to 10.0 μg/kg. The validation results were acceptable, with average recoveries of 78.7–114.0% and relative standard deviations below 14.2%. The method recoveries were closely related to the volume proportion of water in the extractant. Finally, the developed method was applied to real freeze-dried cabbages and four pesticides (propamocarb, imidacloprid, acetamiprid, and thiacloprid) were detected in six samples.https://www.mdpi.com/2304-8158/12/4/699carbamatefreeze-dried cabbagemodified QuEChERSneonicotinoidultra-performance liquid chromatography–tandem mass spectrometry |
| spellingShingle | Bingxin Yang Sheng Wang Wen Ma Guanlin Li Mengling Tu Zhiyong Ma Qinghe Zhang Hongmei Li Xianjiang Li Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry Foods carbamate freeze-dried cabbage modified QuEChERS neonicotinoid ultra-performance liquid chromatography–tandem mass spectrometry |
| title | Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_full | Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_fullStr | Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_full_unstemmed | Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_short | Simultaneous Determination of Neonicotinoid and Carbamate Pesticides in Freeze-Dried Cabbage by Modified QuEChERS and Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_sort | simultaneous determination of neonicotinoid and carbamate pesticides in freeze dried cabbage by modified quechers and ultra performance liquid chromatography tandem mass spectrometry |
| topic | carbamate freeze-dried cabbage modified QuEChERS neonicotinoid ultra-performance liquid chromatography–tandem mass spectrometry |
| url | https://www.mdpi.com/2304-8158/12/4/699 |
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