Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis

Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis

Osteoarthritis is the most common musculoskeletal disease causing chronic disability in adults. Studying cartilage aging, chondrocyte senescence, inflammation, and autophagy mechanisms have identified promising targets and pathways with clinical translatability potential. In this review, we highligh...

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Bibliographic Details
Main Authors: Claire Vinatier, Eduardo Domínguez, Jerome Guicheux, Beatriz Caramés
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Physiology
Subjects:
inflammation
aging
senescence
autophagy
chondrocytes
cartilage
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00706/full

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