Structural Probing with MNase Tethered to Ribosome Assembly Factors Resolves Flexible RNA Regions within the Nascent Pre-Ribosomal RNA

Structural Probing with MNase Tethered to Ribosome Assembly Factors Resolves Flexible RNA Regions within the Nascent Pre-Ribosomal RNA

The synthesis of ribosomes involves the correct folding of the pre-ribosomal RNA within pre-ribosomal particles. The first ribosomal precursor or small subunit processome assembles stepwise on the nascent transcript of the 35S gene. At the earlier stages, the pre-ribosomal particles undergo structur...

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Bibliographic Details
Main Authors: Tom Dielforder, Christina Maria Braun, Fabian Hölzgen, Shuang Li, Mona Thiele, Marina Huber, Uli Ohmayer, Jorge Perez-Fernandez
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Non-Coding RNA
Subjects:
ribosome biogenesis
SSU-processome
<i>S. cerevisiae</i>
structural probing
RNA
Online Access:https://www.mdpi.com/2311-553X/8/1/1

Internet

https://www.mdpi.com/2311-553X/8/1/1

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