Near infrared light fluorescence imaging-guided biomimetic nanoparticles of extracellular vesicles deliver indocyanine green and paclitaxel for hyperthermia combined with chemotherapy against glioma

Near infrared light fluorescence imaging-guided biomimetic nanoparticles of extracellular vesicles deliver indocyanine green and paclitaxel for hyperthermia combined with chemotherapy against glioma

Abstract Background We investigated the therapeutic effect of targeting extracellular vesicles (EVs) loaded with indocyanine green (ICG) and paclitaxel (PTX) on glioma. Methods Raw264.7 cells were harvested to extract EVs for the preparation of ICG/PTX@RGE-EV by electroporation and click chemistry....

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Bibliographic Details
Main Authors: Meng Wang, Chen-Yan Lv, Shu-Ang Li, Jun-Kuan Wang, Wen-Zheng Luo, Pei-Chao Zhao, Xue-You Liu, Ze-Ming Wang, Yang Jiao, Hong-Wei Sun, Yi Zhao, Peng Zhang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Nanobiotechnology
Subjects:
Glioma
Extracellular vesicles
Near infrared light
Indocyanine green
Paclitaxel
RGE
Online Access:https://doi.org/10.1186/s12951-021-00907-3

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