Potential Role of JAK Inhibitors in the Treatment of Systemic Sclerosis-Associated Interstitial Lung Disease: A Narrative Review from Pathogenesis to Real-Life Data

Potential Role of JAK Inhibitors in the Treatment of Systemic Sclerosis-Associated Interstitial Lung Disease: A Narrative Review from Pathogenesis to Real-Life Data

Background: Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is one of the most relevant complications of SSc and the major cause of death. The pathogenesis of SSc-ILD involves a complex interplay of multiple cell types and different molecular pathways, with both inflammation and fi...

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Bibliographic Details
Main Authors: Elisa Fiorentini, Francesco Bonomi, Silvia Peretti, Martina Orlandi, Gemma Lepri, Marco Matucci Cerinic, Silvia Bellando Randone, Serena Guiducci
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Life
Subjects:
systemic sclerosis
interstitial lung disease
JAK inhibitors
autoimmune disease
Online Access:https://www.mdpi.com/2075-1729/12/12/2101

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