Mediterranean Diet: Lipids, Inflammation, and Malaria Infection
The Mediterranean diet (MedDiet) consists of consumption of vegetables and healthy oils and have beneficial effects on metabolic and inflammatory diseases. Our goal here is to discuss the role of fatty acid content in MedDiet, mostly omega-3, omega-6, and omega-9 on malaria. Malaria affects millions...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/21/12/4489 |
| _version_ | 1797564222193795072 |
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| author | Adriana R. Silva Bianca P. T. Moraes Cassiano F. Gonçalves-de-Albuquerque |
| author_facet | Adriana R. Silva Bianca P. T. Moraes Cassiano F. Gonçalves-de-Albuquerque |
| author_sort | Adriana R. Silva |
| collection | DOAJ |
| description | The Mediterranean diet (MedDiet) consists of consumption of vegetables and healthy oils and have beneficial effects on metabolic and inflammatory diseases. Our goal here is to discuss the role of fatty acid content in MedDiet, mostly omega-3, omega-6, and omega-9 on malaria. Malaria affects millions of people around the globe. The parasite Plasmodium causes the disease. The metabolic and inflammatory alterations in the severe forms have damaging consequences to the host. The lipid content in the MedDiet holds anti-inflammatory and pro-resolutive features in the host and have detrimental effects on the Plasmodium. The lipids from the diet impact the balance of pro- and anti-inflammation, thus, lipids intake from the diet is critical to parasite elimination and host tissue damage caused by an immune response. Herein, we go into the cellular and molecular mechanisms and targets of the MedDiet fatty acids in the host and the parasite, reviewing potential benefits of the MedDiet, on inflammation, malaria infection progression, and clinical outcome. |
| first_indexed | 2024-03-10T18:54:20Z |
| format | Article |
| id | doaj.art-75c0f03a2b3a451facb3ed50672ea8d8 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T18:54:20Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-75c0f03a2b3a451facb3ed50672ea8d82023-11-20T04:51:35ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-06-012112448910.3390/ijms21124489Mediterranean Diet: Lipids, Inflammation, and Malaria InfectionAdriana R. Silva0Bianca P. T. Moraes1Cassiano F. Gonçalves-de-Albuquerque2Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro 21040-900, BrazilLaboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro 21040-900, BrazilLaboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro 21040-900, BrazilThe Mediterranean diet (MedDiet) consists of consumption of vegetables and healthy oils and have beneficial effects on metabolic and inflammatory diseases. Our goal here is to discuss the role of fatty acid content in MedDiet, mostly omega-3, omega-6, and omega-9 on malaria. Malaria affects millions of people around the globe. The parasite Plasmodium causes the disease. The metabolic and inflammatory alterations in the severe forms have damaging consequences to the host. The lipid content in the MedDiet holds anti-inflammatory and pro-resolutive features in the host and have detrimental effects on the Plasmodium. The lipids from the diet impact the balance of pro- and anti-inflammation, thus, lipids intake from the diet is critical to parasite elimination and host tissue damage caused by an immune response. Herein, we go into the cellular and molecular mechanisms and targets of the MedDiet fatty acids in the host and the parasite, reviewing potential benefits of the MedDiet, on inflammation, malaria infection progression, and clinical outcome.https://www.mdpi.com/1422-0067/21/12/4489mediterranean dietfatty acidomega-3omega-6omega-9inflammation |
| spellingShingle | Adriana R. Silva Bianca P. T. Moraes Cassiano F. Gonçalves-de-Albuquerque Mediterranean Diet: Lipids, Inflammation, and Malaria Infection International Journal of Molecular Sciences mediterranean diet fatty acid omega-3 omega-6 omega-9 inflammation |
| title | Mediterranean Diet: Lipids, Inflammation, and Malaria Infection |
| title_full | Mediterranean Diet: Lipids, Inflammation, and Malaria Infection |
| title_fullStr | Mediterranean Diet: Lipids, Inflammation, and Malaria Infection |
| title_full_unstemmed | Mediterranean Diet: Lipids, Inflammation, and Malaria Infection |
| title_short | Mediterranean Diet: Lipids, Inflammation, and Malaria Infection |
| title_sort | mediterranean diet lipids inflammation and malaria infection |
| topic | mediterranean diet fatty acid omega-3 omega-6 omega-9 inflammation |
| url | https://www.mdpi.com/1422-0067/21/12/4489 |
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