Achievement of Three Year Remission with Bevacizumab and Irinotecan in Recurrent Glioblastoma Multiforme: A case Report

A 34-year-old man presented to the hospital with right-sided headache. He was diagnosed with GBM. He underwent resection of the tumor with placement of carmustine impregnated wafers. Then he underwent adjuvant chemotherapy with temozolamide. Before the completion of chemotherapy he had a recurrence....

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Main Authors: Abhirami Vivekanandarajah, Balakumar Krishnarasa, Mervat Mourad, Nelly Aoun, Marcel Odaimi
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.4137/CMO.S6525
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author Abhirami Vivekanandarajah
Balakumar Krishnarasa
Mervat Mourad
Nelly Aoun
Marcel Odaimi
author_facet Abhirami Vivekanandarajah
Balakumar Krishnarasa
Mervat Mourad
Nelly Aoun
Marcel Odaimi
author_sort Abhirami Vivekanandarajah
collection DOAJ
description A 34-year-old man presented to the hospital with right-sided headache. He was diagnosed with GBM. He underwent resection of the tumor with placement of carmustine impregnated wafers. Then he underwent adjuvant chemotherapy with temozolamide. Before the completion of chemotherapy he had a recurrence. He underwent re-resection with placement of carmustine impregnated wafers. Subsequently he had eighteen cycles of salvage biochemotherapy with bevacizumab and irinotecan. To date, routine MRI scans of the brain have not shown evidence of recurrence. He continues to be in remission three years after treatment with bevacizumab and irinotecan.
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spelling doaj.art-75c730283abe47f0ba36958daaea8ac52022-12-22T00:51:31ZengSAGE PublishingClinical Medicine Insights: Oncology1179-55492011-01-01510.4137/CMO.S6525Achievement of Three Year Remission with Bevacizumab and Irinotecan in Recurrent Glioblastoma Multiforme: A case ReportAbhirami Vivekanandarajah0Balakumar Krishnarasa1Mervat Mourad2Nelly Aoun3Marcel Odaimi4Staten Island University Hospital, 475 Seaview Avenue, Staten Island, New York 10305.Staten Island University Hospital, 475 Seaview Avenue, Staten Island, New York 10305.Staten Island University Hospital, 475 Seaview Avenue, Staten Island, New York 10305.Staten Island University Hospital, 475 Seaview Avenue, Staten Island, New York 10305.Staten Island University Hospital, 475 Seaview Avenue, Staten Island, New York 10305.A 34-year-old man presented to the hospital with right-sided headache. He was diagnosed with GBM. He underwent resection of the tumor with placement of carmustine impregnated wafers. Then he underwent adjuvant chemotherapy with temozolamide. Before the completion of chemotherapy he had a recurrence. He underwent re-resection with placement of carmustine impregnated wafers. Subsequently he had eighteen cycles of salvage biochemotherapy with bevacizumab and irinotecan. To date, routine MRI scans of the brain have not shown evidence of recurrence. He continues to be in remission three years after treatment with bevacizumab and irinotecan.https://doi.org/10.4137/CMO.S6525
spellingShingle Abhirami Vivekanandarajah
Balakumar Krishnarasa
Mervat Mourad
Nelly Aoun
Marcel Odaimi
Achievement of Three Year Remission with Bevacizumab and Irinotecan in Recurrent Glioblastoma Multiforme: A case Report
Clinical Medicine Insights: Oncology
title Achievement of Three Year Remission with Bevacizumab and Irinotecan in Recurrent Glioblastoma Multiforme: A case Report
title_full Achievement of Three Year Remission with Bevacizumab and Irinotecan in Recurrent Glioblastoma Multiforme: A case Report
title_fullStr Achievement of Three Year Remission with Bevacizumab and Irinotecan in Recurrent Glioblastoma Multiforme: A case Report
title_full_unstemmed Achievement of Three Year Remission with Bevacizumab and Irinotecan in Recurrent Glioblastoma Multiforme: A case Report
title_short Achievement of Three Year Remission with Bevacizumab and Irinotecan in Recurrent Glioblastoma Multiforme: A case Report
title_sort achievement of three year remission with bevacizumab and irinotecan in recurrent glioblastoma multiforme a case report
url https://doi.org/10.4137/CMO.S6525
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AT mervatmourad achievementofthreeyearremissionwithbevacizumabandirinotecaninrecurrentglioblastomamultiformeacasereport
AT nellyaoun achievementofthreeyearremissionwithbevacizumabandirinotecaninrecurrentglioblastomamultiformeacasereport
AT marcelodaimi achievementofthreeyearremissionwithbevacizumabandirinotecaninrecurrentglioblastomamultiformeacasereport