Effects of Age on Long-Term Functional Recovery in Patients with Stroke
<i>Background and objectives:</i> Age might be a determinant that limits functional recovery in patients with stroke. Here, we investigated the effect of age on functional recovery within 30 months after stroke onset. <i>Materials and Methods:</i> This retrospective longitudi...
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MDPI AG
2020-09-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1010-660X/56/9/451 |
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| author | Jae Wan Yoo Bo Young Hong Leechan Jo Joon-Sung Kim Jung Geun Park Bo Kyung Shin Seong Hoon Lim |
| author_facet | Jae Wan Yoo Bo Young Hong Leechan Jo Joon-Sung Kim Jung Geun Park Bo Kyung Shin Seong Hoon Lim |
| author_sort | Jae Wan Yoo |
| collection | DOAJ |
| description | <i>Background and objectives:</i> Age might be a determinant that limits functional recovery in patients with stroke. Here, we investigated the effect of age on functional recovery within 30 months after stroke onset. <i>Materials and Methods:</i> This retrospective longitudinal study enrolled 111 patients with first-ever stroke. Functional recovery was assessed at 2 weeks and at 1, 6, and 30 months after stroke onset using the modified Barthel Index (MBI), modified Rankin Score (mRS), functional ambulation category (FAC), muscle strength, and Mini-Mental State Examination (MMSE). A generalized estimating equation analysis was performed. <i>Results:</i> With the MBI, function improved until 6 months after stroke onset in patients aged <70 years and until 1 month after stroke onset in patients ≥70 years. At 30 months after stroke, there was no significant change of MBI in patients aged <70 years, whereas there was a significant decline in older patients. With the mRS and FAC, function improved until 30 months after stroke onset in patients aged <70 years and until 1 month after stroke onset in older patients. Motor deficit, assessed using the Medical Research Council (MRC), improved significantly until 6 months after stroke onset in patients aged <70 years. There was a significant improvement in cognition (assessed using the MMSE) until 6 months after stroke onset in patients aged <70 years and until 1 month after stroke onset in older patients. <i>Conclusions:</i> Long-term functional recovery occurred for up to 30 months after stroke. Patients aged ≥70 years showed functional decline between 6 and 30 months after onset. These findings could be useful when measuring functional recovery after stroke. |
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| issn | 1010-660X |
| language | English |
| last_indexed | 2024-03-12T09:29:55Z |
| publishDate | 2020-09-01 |
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| series | Medicina |
| spelling | doaj.art-75cd320ae3a04e6daf342dfa9c58de152023-09-02T13:55:38ZengMDPI AGMedicina1010-660X2020-09-015645145110.3390/medicina56090451Effects of Age on Long-Term Functional Recovery in Patients with StrokeJae Wan Yoo0Bo Young Hong1Leechan Jo2Joon-Sung Kim3Jung Geun Park4Bo Kyung Shin5Seong Hoon Lim6Department of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaDepartment of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaDepartment of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaDepartment of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaDepartment of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaDepartment of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaDepartment of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea<i>Background and objectives:</i> Age might be a determinant that limits functional recovery in patients with stroke. Here, we investigated the effect of age on functional recovery within 30 months after stroke onset. <i>Materials and Methods:</i> This retrospective longitudinal study enrolled 111 patients with first-ever stroke. Functional recovery was assessed at 2 weeks and at 1, 6, and 30 months after stroke onset using the modified Barthel Index (MBI), modified Rankin Score (mRS), functional ambulation category (FAC), muscle strength, and Mini-Mental State Examination (MMSE). A generalized estimating equation analysis was performed. <i>Results:</i> With the MBI, function improved until 6 months after stroke onset in patients aged <70 years and until 1 month after stroke onset in patients ≥70 years. At 30 months after stroke, there was no significant change of MBI in patients aged <70 years, whereas there was a significant decline in older patients. With the mRS and FAC, function improved until 30 months after stroke onset in patients aged <70 years and until 1 month after stroke onset in older patients. Motor deficit, assessed using the Medical Research Council (MRC), improved significantly until 6 months after stroke onset in patients aged <70 years. There was a significant improvement in cognition (assessed using the MMSE) until 6 months after stroke onset in patients aged <70 years and until 1 month after stroke onset in older patients. <i>Conclusions:</i> Long-term functional recovery occurred for up to 30 months after stroke. Patients aged ≥70 years showed functional decline between 6 and 30 months after onset. These findings could be useful when measuring functional recovery after stroke.https://www.mdpi.com/1010-660X/56/9/451strokefunctional recoveryoutcomeage effect |
| spellingShingle | Jae Wan Yoo Bo Young Hong Leechan Jo Joon-Sung Kim Jung Geun Park Bo Kyung Shin Seong Hoon Lim Effects of Age on Long-Term Functional Recovery in Patients with Stroke Medicina stroke functional recovery outcome age effect |
| title | Effects of Age on Long-Term Functional Recovery in Patients with Stroke |
| title_full | Effects of Age on Long-Term Functional Recovery in Patients with Stroke |
| title_fullStr | Effects of Age on Long-Term Functional Recovery in Patients with Stroke |
| title_full_unstemmed | Effects of Age on Long-Term Functional Recovery in Patients with Stroke |
| title_short | Effects of Age on Long-Term Functional Recovery in Patients with Stroke |
| title_sort | effects of age on long term functional recovery in patients with stroke |
| topic | stroke functional recovery outcome age effect |
| url | https://www.mdpi.com/1010-660X/56/9/451 |
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