A synthetic biosensor to detect peroxisomal acetyl-CoA concentration for compartmentalized metabolic engineering

Background Sub-cellular compartmentalization is used by cells to create favorable microenvironments for various metabolic reactions. These compartments concentrate enzymes, separate competing metabolic reactions, and isolate toxic intermediates. Such advantages have been recently harnessed by metabo...

Full description

Bibliographic Details
Main Authors: Herbert M. Huttanus, Ryan S. Senger
Format: Article
Language:English
Published: PeerJ Inc. 2020-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/9805.pdf