Can Exercise Enhance the Efficacy of Checkpoint Inhibition by Modulating Anti-Tumor Immunity?

Can Exercise Enhance the Efficacy of Checkpoint Inhibition by Modulating Anti-Tumor Immunity?

Immune checkpoint inhibition (ICI) has revolutionized cancer therapy. However, response to ICI is often limited to selected subsets of patients or not durable. Tumors that are non-responsive to checkpoint inhibition are characterized by low anti-tumoral immune cell infiltration and a highly immunosu...

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Bibliographic Details
Main Authors: Christina Brummer, Tobias Pukrop, Joachim Wiskemann, Christina Bruss, Ines Ugele, Kathrin Renner
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
physical activity (PA)
exercise
cancer
immune checkpoint inhibition (ICI)
PD-1
PD-L1
Online Access:https://www.mdpi.com/2072-6694/15/18/4668

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