Protective effects of human umbilical cord mesenchymal stem cells on retinal ganglion cells in mice with acute ocular hypertension

Protective effects of human umbilical cord mesenchymal stem cells on retinal ganglion cells in mice with acute ocular hypertension

AIM: To observe the protective effect of human umbilical cord mesenchymal stem cells (hucMSCs) on retinal ganglion cells (RGCs) injury in mice with acute ocular hypertension (AOH). METHODS: Fifty-six adult male C57BL/6 mice were randomly divided into four groups: normal group, AOH group, hucMSCs gro...

Full description

Bibliographic Details
Main Authors:	Rui Liu, Qi Shi, Hong Yang, Xiao-Yuan Sha, Guo-Cheng Yu, Lian Liu, Jing-Xiang Zhong
Format:	Article
Language:	English
Published:	Press of International Journal of Ophthalmology (IJO PRESS) 2021-02-01
Series:	International Journal of Ophthalmology
Subjects:	human umbilical cord mesenchymal stem cells glaucoma acute ocular hypertension retinal ganglion cells
Online Access:	http://ies.ijo.cn/en_publish/2021/2/20210203.pdf

Similar Items

Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus
by: Ashish Bhandari, et al.
Published: (2019-09-01)

Acute ocular hypertension induced pyropotosis in rat retinal ganglion cells and protective effect of inhibiting Caspase-1 in rat model
by: SUN Yulin, et al.
Published: (2022-04-01)

Intravenous infusion of small umbilical cord mesenchymal stem cells could enhance safety and delay retinal degeneration in RCS rats
by: Qingling Liang, et al.
Published: (2022-02-01)

MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma
by: Mohammad Harun-Or-Rashid, et al.
Published: (2020-07-01)

Effects and mechanisms of curcumin on apoptosis of retinal ganglion cells in chronic ocular hypertension rats
by: Wan-Jing Xu, et al.
Published: (2023-12-01)

In vitro study of various factors in isolation, expansion and differentiation of mesenchymal stem cells from human umbilical cord
by: Salehinejad, Parvin
Published: (2012)

Lipopolysaccharide’s Cytotoxicity on Human Umbilical Cord Mesenchymal Stem Cells
by: Mefina Kuntjoro, et al.
Published: (2022-03-01)

Comparison of cytokine profile in mesenchymal stem cells derived from human umbilical cord and placenta
by: Zhang Kun, Li Fang, Xiao Dongjie, Gao Dehai, Sun Zhijun, Liu Hua
Published: (2022-10-01)

Tools and Biomarkers for the Study of Retinal Ganglion Cell Degeneration
by: Ciriaco Corral-Domenge, et al.
Published: (2022-04-01)

On the Generation and Regeneration of Retinal Ganglion Cells
by: Viviane M. Oliveira-Valença, et al.
Published: (2020-09-01)

Isolation and Characterization of Human Mesenchymal Stem Cells Derived from Human Umbilical Cord Wharton�s Jelly and Amniotic Membrane
by: T Pirjali, et al.
Published: (2013-07-01)

Study of internalization and viability of multimodal nanoparticles for labeling of human umbilical cord mesenchymal stem cells
by: Liza Aya Mabuchi Miyaki, et al.
Published: (2012-06-01)

Study of internalization and viability of multimodal nanoparticles for labeling of human umbilical cord mesenchymal stem cells
by: Liza Aya Mabuchi Miyaki, et al.
Published: (2012-06-01)

Shared and Differential Retinal Responses against Optic Nerve Injury and Ocular Hypertension
by: Manuel Vidal-Sanz, et al.
Published: (2017-04-01)

Umbilical cord derived mesenchymal stem cell implantation in retinitis pigmentosa: a 6-month follow-up results of a phase 3 trial
by: Neslihan Sinim Kahraman, et al.
Published: (2020-09-01)

In vivo Regeneration of Ganglion Cells for Vision Restoration in Mammalian Retinas
by: Dongchang Xiao, et al.
Published: (2021-10-01)

Role of Oxidative Stress in Ocular Diseases Associated with Retinal Ganglion Cells Degeneration
by: Eugene Yu-Chuan Kang, et al.
Published: (2021-12-01)

PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesis
by: Jingyi Luo, et al.
Published: (2023-07-01)

Real-Time Imaging of Retinal Ganglion Cell Apoptosis
by: Timothy E. Yap, et al.
Published: (2018-06-01)

Risk Factors for Retinal Ganglion Cell Distress in Glaucoma and Neuroprotective Potential Intervention
by: Stefania Vernazza, et al.
Published: (2021-07-01)

Mesenchymal stem cells isolated from peripheral blood and umbilical cord Wharton’s jelly
by: Trivanović Drenka, et al.
Published: (2013-01-01)

Interleukins Profiling in Umbilical Cord Mesenchymal Stem Cell-Derived Secretome
by: Chouw A, et al.
Published: (2022-04-01)

Application of stem cell transplantation in repair of the retinal ganglion cells injury
by: Xin Rong, et al.
Published: (2014-07-01)

Stem Cell-Based Regeneration and Restoration for Retinal Ganglion Cell: Recent Advancements and Current Challenges
by: Jingxue Zhang, et al.
Published: (2021-07-01)

Retinal ganglion cells adapt to ionic stress in experimental glaucoma
by: Andrew M. Boal, et al.
Published: (2023-03-01)

Cell-Based Neuroprotection of Retinal Ganglion Cells in Animal Models of Optic Neuropathies
by: Yue Hu, et al.
Published: (2021-11-01)

Umbilical cord-derived mesenchymal stem cells cultured in the MCL medium for aplastic anemia therapy
by: Chuan He, et al.
Published: (2023-08-01)

The role of TRPV4 in the regulation of retinal ganglion cells apoptosis in rat and mouse
by: Yi Wang, et al.
Published: (2023-07-01)

Differentiation of retinal ganglion cells from induced pluripotent stem cells: a review
by: Shang-Li Ji, et al.
Published: (2019-01-01)

Quercetin Declines Apoptosis, Ameliorates Mitochondrial Function and Improves Retinal Ganglion Cell Survival and Function in In Vivo Model of Glaucoma in Rat and Retinal Ganglion Cell Culture In Vitro
by: Feng-Juan Gao, et al.
Published: (2017-09-01)

Comparative study of the biological properties of foetal and placental distal ends of human umbilical cord wharton's jelly mesenchymal stem cells
by: Yusoff, Zuraidah
Published: (2015)

Mesenchymal Stem or Stromal Cells from Amnion and Umbilical Cord Tissue and Their Potential for Clinical Applications
by: Heinz Redl, et al.
Published: (2012-11-01)

Preparation of pigment epithelial-derived factor-modified human umbilical cord-derived mesenchymal stem cells
by: Hui Wen, et al.
Published: (2017-07-01)

Modeling Retinal Ganglion Cell Dysfunction in Optic Neuropathies
by: Vittorio Porciatti, et al.
Published: (2021-06-01)

Evaluation of Macular and Retinal Ganglion Cell Count Estimates for Detecting and Staging Glaucoma
by: Yali Wu, et al.
Published: (2021-10-01)

Comparison of proliferative and multilineage differentiation potentials of cord matrix, cord blood, and bone marrow mesenchymal stem cells
by: Shetty Prathibha, et al.
Published: (2010-01-01)

Post-calving umbilical cord tissue offcut: A potential source for the isolation of bovine mesenchymal stem cells
by: Parishma Debbarma, et al.
Published: (2020-12-01)

Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cell Therapy for Rheumatoid Arthritis Patients: A Prospective Phase I/II Study
by: Wang L, et al.
Published: (2019-12-01)

Application of cells of cord blood and umbilical cord: achievements, challenges and perspectives
by: I. V. Gilevich, et al.
Published: (2022-06-01)

Silibinin declines blue light-induced apoptosis and inflammation through MEK/ERK/CREB of retinal ganglion cells
by: Ying Shen, et al.
Published: (2019-12-01)