Marine Peroxy Sesquiterpenoids Induce Apoptosis by Modulation of Nrf2-ARE Signaling in HCT116 Colon Cancer Cells

Marine Peroxy Sesquiterpenoids Induce Apoptosis by Modulation of Nrf2-ARE Signaling in HCT116 Colon Cancer Cells

Our current study demonstrated that the marine peroxy sesquiterpenoids isolated from the Okinawan soft coral Sinularia sp. have an antitumor activity in human colon cancer cell (HCT) 116 colon cancer cells with their induction of apoptosis due to H2O2 production derived from the compounds. This stud...

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Bibliographic Details
Main Authors:	Junsei Taira, Haruna Miyazato, Katsuhiro Ueda
Format:	Article
Language:	English
Published:	MDPI AG 2018-09-01
Series:	Marine Drugs
Subjects:	free radical peroxy sesquiterpenoid apoptosis Nrf2-ARE signaling HCT116 colon cancer cells soft coral Sinularia sp.
Online Access:	http://www.mdpi.com/1660-3397/16/10/347

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