Advanced nasopharyngeal carcinoma in children
Nasopharyngeal carcinoma (NPC) is the most familiar cancer originating in the nasopharynx, and not uncommonly found in the head and neck region in adults. Under appropriate and effective treatment, the outcome subsequent to medical intervention can be relatively good in adults with nasopharyngeal ca...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-09-01
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| Series: | Journal of Cancer Research and Practice |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2311300616301239 |
| _version_ | 1818036289983741952 |
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| author | Wan-Chen Kao Jiann-Shiuh Chen Chia-Jui Yen |
| author_facet | Wan-Chen Kao Jiann-Shiuh Chen Chia-Jui Yen |
| author_sort | Wan-Chen Kao |
| collection | DOAJ |
| description | Nasopharyngeal carcinoma (NPC) is the most familiar cancer originating in the nasopharynx, and not uncommonly found in the head and neck region in adults. Under appropriate and effective treatment, the outcome subsequent to medical intervention can be relatively good in adults with nasopharyngeal carcinoma. However, NPC is very uncommon in children younger than 10 years, and its incidence increases gradually with patient age. In general, NPC may be more aggressive in character, with frequent distant metastasis while initial diagnosis in children. We reported the case of a 12-year-old girl with advanced nasopharyngeal carcinoma, who was refractory to multiple chemotherapy regimens. We herein have provided a summary review of the literature regarding the incidence, characteristics, treatment and outcome of nasopharyngeal carcinoma in children, in the hopes of encouraging further investigations that will create additional treatment options for those who suffer NPR at any age. |
| first_indexed | 2024-12-10T07:08:36Z |
| format | Article |
| id | doaj.art-75ddb9bf3a4a4d31ab2677202627f6ac |
| institution | Directory Open Access Journal |
| issn | 2311-3006 |
| language | English |
| last_indexed | 2024-12-10T07:08:36Z |
| publishDate | 2016-09-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cancer Research and Practice |
| spelling | doaj.art-75ddb9bf3a4a4d31ab2677202627f6ac2022-12-22T01:58:07ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062016-09-0133848810.1016/j.jcrpr.2016.05.007Advanced nasopharyngeal carcinoma in childrenWan-Chen Kao0Jiann-Shiuh Chen1Chia-Jui Yen2Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanDivision of Hematology, Department of Pediatrics, National Cheng Kung University Hospital, Tainan, TaiwanDivision of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanNasopharyngeal carcinoma (NPC) is the most familiar cancer originating in the nasopharynx, and not uncommonly found in the head and neck region in adults. Under appropriate and effective treatment, the outcome subsequent to medical intervention can be relatively good in adults with nasopharyngeal carcinoma. However, NPC is very uncommon in children younger than 10 years, and its incidence increases gradually with patient age. In general, NPC may be more aggressive in character, with frequent distant metastasis while initial diagnosis in children. We reported the case of a 12-year-old girl with advanced nasopharyngeal carcinoma, who was refractory to multiple chemotherapy regimens. We herein have provided a summary review of the literature regarding the incidence, characteristics, treatment and outcome of nasopharyngeal carcinoma in children, in the hopes of encouraging further investigations that will create additional treatment options for those who suffer NPR at any age.http://www.sciencedirect.com/science/article/pii/S2311300616301239Advanced nasopharyngeal carcinomaChildrenOutcome |
| spellingShingle | Wan-Chen Kao Jiann-Shiuh Chen Chia-Jui Yen Advanced nasopharyngeal carcinoma in children Journal of Cancer Research and Practice Advanced nasopharyngeal carcinoma Children Outcome |
| title | Advanced nasopharyngeal carcinoma in children |
| title_full | Advanced nasopharyngeal carcinoma in children |
| title_fullStr | Advanced nasopharyngeal carcinoma in children |
| title_full_unstemmed | Advanced nasopharyngeal carcinoma in children |
| title_short | Advanced nasopharyngeal carcinoma in children |
| title_sort | advanced nasopharyngeal carcinoma in children |
| topic | Advanced nasopharyngeal carcinoma Children Outcome |
| url | http://www.sciencedirect.com/science/article/pii/S2311300616301239 |
| work_keys_str_mv | AT wanchenkao advancednasopharyngealcarcinomainchildren AT jiannshiuhchen advancednasopharyngealcarcinomainchildren AT chiajuiyen advancednasopharyngealcarcinomainchildren |