Impact of DNA damage repair alterations on prostate cancer progression and metastasis

Impact of DNA damage repair alterations on prostate cancer progression and metastasis

Prostate cancer is among the most common diseases worldwide. Despite recent progress with treatments, patients with advanced prostate cancer have poor outcomes and there is a high unmet need in this population. Understanding molecular determinants underlying prostate cancer and the aggressive phenot...

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Bibliographic Details
Main Authors: Natalia Lukashchuk, Alan Barnicle, Carrie A. Adelman, Joshua Armenia, Jinyu Kang, J. Carl Barrett, Elizabeth A. Harrington
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
DNA damage response
homologous recombination repair
alterations
prognosis
prostate cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1162644/full

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