Mechanosensitive TRPV4 channel guides maturation and organization of the bilayered mammary epithelium

Abstract Biophysical cues from the cell microenvironment are detected by mechanosensitive components at the cell surface. Such machineries convert physical information into biochemical signaling cascades within cells, subsequently leading to various cellular responses in a stimulus-dependent manner....

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Bibliographic Details
Main Authors: Kärki Tytti, Koskimäki Sanna, Guenther Carla, Pirhonen Jonatan, Rajakylä Kaisa, Tojkander Sari
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-57346-x