A case of livedoid vasculopathy, a thrombotic occlusive vasculopathy

Abstract Livedoid vasculopathy (LV) is a rare thrombotic occlusive vasculopathy presenting with chronic relapsing‐remitting bilateral painful skin ulcerations predominating on the ankles and dorsal surface of the feet. LV can be idiopathic or secondary to endothelial dysfunction, rheological disorde...

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Main Authors: Anais Huot, Christa‐Maria Maniu, Sofia Bogiatzi, Daniel Hohl, Lorenzo Alberio, Gregoire Stalder
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:JEADV Clinical Practice
Subjects:
Online Access:https://doi.org/10.1002/jvc2.4
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author Anais Huot
Christa‐Maria Maniu
Sofia Bogiatzi
Daniel Hohl
Lorenzo Alberio
Gregoire Stalder
author_facet Anais Huot
Christa‐Maria Maniu
Sofia Bogiatzi
Daniel Hohl
Lorenzo Alberio
Gregoire Stalder
author_sort Anais Huot
collection DOAJ
description Abstract Livedoid vasculopathy (LV) is a rare thrombotic occlusive vasculopathy presenting with chronic relapsing‐remitting bilateral painful skin ulcerations predominating on the ankles and dorsal surface of the feet. LV can be idiopathic or secondary to endothelial dysfunction, rheological disorder, haemostatic or fibrinolytic pathology. We describe the case of a 49‐year‐old patient with LV and summarise the current knowledge on epidemiology, risk factors, and treatment of this rare condition. It is important to differentiate LV from vasculitic disorders, the management of the latter being based on immunosuppression, whereas the treatment of LV is based on anticoagulant or antiplatelet therapy.
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spelling doaj.art-75e0aa9cce334ce4b281960d3555ad5f2022-12-22T04:35:29ZengWileyJEADV Clinical Practice2768-65662022-03-0111454810.1002/jvc2.4A case of livedoid vasculopathy, a thrombotic occlusive vasculopathyAnais Huot0Christa‐Maria Maniu1Sofia Bogiatzi2Daniel Hohl3Lorenzo Alberio4Gregoire Stalder5Service and Central Laboratory of Hematology Lausanne University Hospital and University of Lausanne Lausanne SwitzerlandService of Dermatology Lausanne University Hospital and University of Lausanne Lausanne SwitzerlandService of Dermatology Lausanne University Hospital and University of Lausanne Lausanne SwitzerlandService of Dermatology Lausanne University Hospital and University of Lausanne Lausanne SwitzerlandService and Central Laboratory of Hematology Lausanne University Hospital and University of Lausanne Lausanne SwitzerlandService and Central Laboratory of Hematology Lausanne University Hospital and University of Lausanne Lausanne SwitzerlandAbstract Livedoid vasculopathy (LV) is a rare thrombotic occlusive vasculopathy presenting with chronic relapsing‐remitting bilateral painful skin ulcerations predominating on the ankles and dorsal surface of the feet. LV can be idiopathic or secondary to endothelial dysfunction, rheological disorder, haemostatic or fibrinolytic pathology. We describe the case of a 49‐year‐old patient with LV and summarise the current knowledge on epidemiology, risk factors, and treatment of this rare condition. It is important to differentiate LV from vasculitic disorders, the management of the latter being based on immunosuppression, whereas the treatment of LV is based on anticoagulant or antiplatelet therapy.https://doi.org/10.1002/jvc2.4antiaggregationchronic ankle ulcerslivedoid vasculopathythrombotic occlusive vasculopathy
spellingShingle Anais Huot
Christa‐Maria Maniu
Sofia Bogiatzi
Daniel Hohl
Lorenzo Alberio
Gregoire Stalder
A case of livedoid vasculopathy, a thrombotic occlusive vasculopathy
JEADV Clinical Practice
antiaggregation
chronic ankle ulcers
livedoid vasculopathy
thrombotic occlusive vasculopathy
title A case of livedoid vasculopathy, a thrombotic occlusive vasculopathy
title_full A case of livedoid vasculopathy, a thrombotic occlusive vasculopathy
title_fullStr A case of livedoid vasculopathy, a thrombotic occlusive vasculopathy
title_full_unstemmed A case of livedoid vasculopathy, a thrombotic occlusive vasculopathy
title_short A case of livedoid vasculopathy, a thrombotic occlusive vasculopathy
title_sort case of livedoid vasculopathy a thrombotic occlusive vasculopathy
topic antiaggregation
chronic ankle ulcers
livedoid vasculopathy
thrombotic occlusive vasculopathy
url https://doi.org/10.1002/jvc2.4
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