Nanoformulation and Evaluation of Oral Berberine-Loaded Liposomes

Nanoformulation and Evaluation of Oral Berberine-Loaded Liposomes

Berberine (BBR) is a poorly water-soluble quaternary isoquinoline alkaloid of plant origin with potential uses in the drug therapy of hypercholesterolemia. To tackle the limitations associated with the oral therapeutic use of BBR (such as a first-pass metabolism and poor absorption), BBR-loaded lipo...

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Bibliographic Details
Main Authors: Thuan Thi Duong, Antti Isomäki, Urve Paaver, Ivo Laidmäe, Arvo Tõnisoo, Tran Thi Hai Yen, Karin Kogermann, Ain Raal, Jyrki Heinämäki, Thi-Minh-Hue Pham
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
berberine
poorly water-soluble alkaloid
liposomes
ethanol-injection
thin-film hydration
Online Access:https://www.mdpi.com/1420-3049/26/9/2591

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