Mechanisms of Demyelination and Remyelination Strategies for Multiple Sclerosis

Mechanisms of Demyelination and Remyelination Strategies for Multiple Sclerosis

All currently licensed medications for multiple sclerosis (MS) target the immune system. Albeit promising preclinical results demonstrated disease amelioration and remyelination enhancement via modulating oligodendrocyte lineage cells, most drug candidates showed only modest or no effects in human c...

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Bibliographic Details
Main Authors: Xinda Zhao, Claire Jacob
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
remyelination
immune cells
oligodendrocytes
transcription factors
epigenetics
Online Access:https://www.mdpi.com/1422-0067/24/7/6373

Internet

https://www.mdpi.com/1422-0067/24/7/6373

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