Comparison of Diagnostic Performance between Classic and Modified Abbreviated Breast MRI and the MRI Features Affecting Their Diagnostic Performance
Abbreviated breast magnetic resonance imaging (AB-MRI) has emerged as a supplementary screening tool, though protocols have not been standardized. The purpose of this study was to compare the diagnostic performance of modified and classic AB-MRI and determine MRI features affecting their diagnostic...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/14/3/282 |
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| author | Subin Lee Eun Jung Choi Hyemi Choi Jung Hee Byon |
| author_facet | Subin Lee Eun Jung Choi Hyemi Choi Jung Hee Byon |
| author_sort | Subin Lee |
| collection | DOAJ |
| description | Abbreviated breast magnetic resonance imaging (AB-MRI) has emerged as a supplementary screening tool, though protocols have not been standardized. The purpose of this study was to compare the diagnostic performance of modified and classic AB-MRI and determine MRI features affecting their diagnostic performance. Classic AB-MRI included one pre- and two post-contrast T1-weighted imaging (T1WI) scans, while modified AB-MRI included a delayed post-contrast axial T1WI scan and an axial T2-weighted interpolated scan obtained between the second and third post-contrast T1WI scans. Four radiologists (two specialists and two non-specialists) independently categorized the lesions. The MRI features investigated were lesion size, lesion type, and background parenchymal enhancement (BPE). The Wilcoxon rank-sum test, Fisher’s exact test, and bootstrap-based test were used for statistical analysis. The average area under the curve (AUC) for modified AB-MRI was significantly greater than that for classic AB-MRI (0.76 vs. 0.70, <i>p</i> = 0.010) in all reader evaluations, with a similar trend in specialist evaluations (0.83 vs. 0.76, <i>p</i> = 0.004). Modified AB-MRI demonstrated increased AUCs and better diagnostic performance than classic AB-MRI, especially for lesion size > 10 mm (<i>p</i> = 0.018) and mass lesion type (<i>p</i> = 0.014) in specialist evaluations and lesion size > 10 mm (<i>p</i> = 0.003) and mild (<i>p</i> = 0.026) or moderate BPE (<i>p</i> = 0.010) in non-specialist evaluations. |
| first_indexed | 2024-03-08T03:58:43Z |
| format | Article |
| id | doaj.art-75f4d75217cf477f9027cc7bd70702f8 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-08T03:58:43Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-75f4d75217cf477f9027cc7bd70702f82024-02-09T15:10:05ZengMDPI AGDiagnostics2075-44182024-01-0114328210.3390/diagnostics14030282Comparison of Diagnostic Performance between Classic and Modified Abbreviated Breast MRI and the MRI Features Affecting Their Diagnostic PerformanceSubin Lee0Eun Jung Choi1Hyemi Choi2Jung Hee Byon3Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju 54907, Jellabuk-Do, Republic of KoreaDepartment of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju 54907, Jellabuk-Do, Republic of KoreaDepartment of Statistics and Institute of Applied Statistics, Jeonbuk National University, Jeonju 54896, Jellabuk-Do, Republic of KoreaDepartment of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44610, Republic of KoreaAbbreviated breast magnetic resonance imaging (AB-MRI) has emerged as a supplementary screening tool, though protocols have not been standardized. The purpose of this study was to compare the diagnostic performance of modified and classic AB-MRI and determine MRI features affecting their diagnostic performance. Classic AB-MRI included one pre- and two post-contrast T1-weighted imaging (T1WI) scans, while modified AB-MRI included a delayed post-contrast axial T1WI scan and an axial T2-weighted interpolated scan obtained between the second and third post-contrast T1WI scans. Four radiologists (two specialists and two non-specialists) independently categorized the lesions. The MRI features investigated were lesion size, lesion type, and background parenchymal enhancement (BPE). The Wilcoxon rank-sum test, Fisher’s exact test, and bootstrap-based test were used for statistical analysis. The average area under the curve (AUC) for modified AB-MRI was significantly greater than that for classic AB-MRI (0.76 vs. 0.70, <i>p</i> = 0.010) in all reader evaluations, with a similar trend in specialist evaluations (0.83 vs. 0.76, <i>p</i> = 0.004). Modified AB-MRI demonstrated increased AUCs and better diagnostic performance than classic AB-MRI, especially for lesion size > 10 mm (<i>p</i> = 0.018) and mass lesion type (<i>p</i> = 0.014) in specialist evaluations and lesion size > 10 mm (<i>p</i> = 0.003) and mild (<i>p</i> = 0.026) or moderate BPE (<i>p</i> = 0.010) in non-specialist evaluations.https://www.mdpi.com/2075-4418/14/3/282breast neoplasmmagnetic resonance imagingscreeningarea under the curvesensitivityspecificity |
| spellingShingle | Subin Lee Eun Jung Choi Hyemi Choi Jung Hee Byon Comparison of Diagnostic Performance between Classic and Modified Abbreviated Breast MRI and the MRI Features Affecting Their Diagnostic Performance Diagnostics breast neoplasm magnetic resonance imaging screening area under the curve sensitivity specificity |
| title | Comparison of Diagnostic Performance between Classic and Modified Abbreviated Breast MRI and the MRI Features Affecting Their Diagnostic Performance |
| title_full | Comparison of Diagnostic Performance between Classic and Modified Abbreviated Breast MRI and the MRI Features Affecting Their Diagnostic Performance |
| title_fullStr | Comparison of Diagnostic Performance between Classic and Modified Abbreviated Breast MRI and the MRI Features Affecting Their Diagnostic Performance |
| title_full_unstemmed | Comparison of Diagnostic Performance between Classic and Modified Abbreviated Breast MRI and the MRI Features Affecting Their Diagnostic Performance |
| title_short | Comparison of Diagnostic Performance between Classic and Modified Abbreviated Breast MRI and the MRI Features Affecting Their Diagnostic Performance |
| title_sort | comparison of diagnostic performance between classic and modified abbreviated breast mri and the mri features affecting their diagnostic performance |
| topic | breast neoplasm magnetic resonance imaging screening area under the curve sensitivity specificity |
| url | https://www.mdpi.com/2075-4418/14/3/282 |
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