A quantitative comparison of single-cell whole genome amplification methods.
Single-cell sequencing is emerging as an important tool for studies of genomic heterogeneity. Whole genome amplification (WGA) is a key step in single-cell sequencing workflows and a multitude of methods have been introduced. Here, we compare three state-of-the-art methods on both bulk and single-ce...
Main Authors: | Charles F A de Bourcy, Iwijn De Vlaminck, Jad N Kanbar, Jianbin Wang, Charles Gawad, Stephen R Quake |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4138190?pdf=render |
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