Data supporting the regulation of FOXC2 in podocyte dysfunction
This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat glomeruli. It also contains information on the effect of the overexpression of transcription factor FOXC2 on the ratio of F- and G-actin and the...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-03-01
|
| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340915004175 |
| _version_ | 1818900104111718400 |
|---|---|
| author | Neeta Datta Sonja Lindfors Naoyuki Miura Moin A. Saleem Sanna Lehtonen |
| author_facet | Neeta Datta Sonja Lindfors Naoyuki Miura Moin A. Saleem Sanna Lehtonen |
| author_sort | Neeta Datta |
| collection | DOAJ |
| description | This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat glomeruli. It also contains information on the effect of the overexpression of transcription factor FOXC2 on the ratio of F- and G-actin and the expression level of ZO-1 in differentiated human podocytes. The article also shows data on the effect of treatments of differentiated podocytes with various factors associated with obesity and diabetes on the expression level of FOXC2. The detailed interpretation of these data and other aspects of podocyte injury mediated by upregulation of FOXC2 can be found in “Overexpression of transcription factor FOXC2 in cultured human podocytes upregulates injury markers and increases motility [1]. |
| first_indexed | 2024-12-19T19:58:33Z |
| format | Article |
| id | doaj.art-75f8e88dc801400da20d4e82ddfafb03 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-19T19:58:33Z |
| publishDate | 2016-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-75f8e88dc801400da20d4e82ddfafb032022-12-21T20:07:44ZengElsevierData in Brief2352-34092016-03-016514520Data supporting the regulation of FOXC2 in podocyte dysfunctionNeeta Datta0Sonja Lindfors1Naoyuki Miura2Moin A. Saleem3Sanna Lehtonen4Department of Pathology, University of Helsinki, 00290 Helsinki, FinlandDepartment of Pathology, University of Helsinki, 00290 Helsinki, FinlandDepartment of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu 431-3192, JapanAcademic and Children’s Renal Unit, Dorothy Hodgkin Building, Bristol BS1, United KingdomDepartment of Pathology, University of Helsinki, 00290 Helsinki, Finland; Corresponding author.This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat glomeruli. It also contains information on the effect of the overexpression of transcription factor FOXC2 on the ratio of F- and G-actin and the expression level of ZO-1 in differentiated human podocytes. The article also shows data on the effect of treatments of differentiated podocytes with various factors associated with obesity and diabetes on the expression level of FOXC2. The detailed interpretation of these data and other aspects of podocyte injury mediated by upregulation of FOXC2 can be found in “Overexpression of transcription factor FOXC2 in cultured human podocytes upregulates injury markers and increases motility [1].http://www.sciencedirect.com/science/article/pii/S2352340915004175 |
| spellingShingle | Neeta Datta Sonja Lindfors Naoyuki Miura Moin A. Saleem Sanna Lehtonen Data supporting the regulation of FOXC2 in podocyte dysfunction Data in Brief |
| title | Data supporting the regulation of FOXC2 in podocyte dysfunction |
| title_full | Data supporting the regulation of FOXC2 in podocyte dysfunction |
| title_fullStr | Data supporting the regulation of FOXC2 in podocyte dysfunction |
| title_full_unstemmed | Data supporting the regulation of FOXC2 in podocyte dysfunction |
| title_short | Data supporting the regulation of FOXC2 in podocyte dysfunction |
| title_sort | data supporting the regulation of foxc2 in podocyte dysfunction |
| url | http://www.sciencedirect.com/science/article/pii/S2352340915004175 |
| work_keys_str_mv | AT neetadatta datasupportingtheregulationoffoxc2inpodocytedysfunction AT sonjalindfors datasupportingtheregulationoffoxc2inpodocytedysfunction AT naoyukimiura datasupportingtheregulationoffoxc2inpodocytedysfunction AT moinasaleem datasupportingtheregulationoffoxc2inpodocytedysfunction AT sannalehtonen datasupportingtheregulationoffoxc2inpodocytedysfunction |