Linoleic acid induces human ovarian granulosa cell inflammation and apoptosis through the ER-FOXO1-ROS-NFκB pathway

Linoleic acid induces human ovarian granulosa cell inflammation and apoptosis through the ER-FOXO1-ROS-NFκB pathway

Abstract Polycystic ovary syndrome (PCOS) is a complex reproductive endocrinological disorder influenced by a combination of genetic and environmental factors. Linoleic acid (LA) is a widely consumed ω-6 polyunsaturated fatty acid, accounting for approximately 80% of daily fatty acid intake. Buildin...

Full description

Bibliographic Details
Main Authors: Wenying Zhang, Fuju Wu
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Linoleic acid
Granulosa cell
Dietary fatty acids
Polycystic ovary syndrome
Apoptosis
Estrogen receptor
Online Access:https://doi.org/10.1038/s41598-024-56970-x

Similar Items

Similar Items