Nanosponges: A Novel Class of Drug Delivery System - Review
ABSTRACT - Effective targeted drug delivery systems have been a dream for a long time, but it has been largely frustrated by the complex chemistry that is involved in the development of new systems. The invention of nanosponges has become a significant step toward overcoming these problems. Nanospon...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-01-01
|
Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/12535 |
_version_ | 1797762458506493952 |
---|---|
author | Selvamuthukumar S Anandam S Kannan Krishnamoorthy Manavalan Rajappan |
author_facet | Selvamuthukumar S Anandam S Kannan Krishnamoorthy Manavalan Rajappan |
author_sort | Selvamuthukumar S |
collection | DOAJ |
description | ABSTRACT - Effective targeted drug delivery systems have been a dream for a long time, but it has been largely frustrated by the complex chemistry that is involved in the development of new systems. The invention of nanosponges has become a significant step toward overcoming these problems. Nanosponges are tiny sponges with a size of about a virus, which can be filled with a wide variety of drugs. These tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner. Because the drug can be released at the specific target site instead of circulating throughout the body it will be more effective for a particular given dosage. Another important character of these sponges is their aqueous solubility; this allows the use of these systems effectively for drugs with poor solubility.
This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page. |
first_indexed | 2024-03-12T19:27:40Z |
format | Article |
id | doaj.art-760411eafd384cc58134fc071bee8184 |
institution | Directory Open Access Journal |
issn | 1482-1826 |
language | English |
last_indexed | 2024-03-12T19:27:40Z |
publishDate | 2012-01-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Journal of Pharmacy & Pharmaceutical Sciences |
spelling | doaj.art-760411eafd384cc58134fc071bee81842023-08-02T04:46:40ZengFrontiers Media S.A.Journal of Pharmacy & Pharmaceutical Sciences1482-18262012-01-0115110.18433/J3K308Nanosponges: A Novel Class of Drug Delivery System - ReviewSelvamuthukumar S0Anandam S1Kannan KrishnamoorthyManavalan RajappanDepartment of Pharmacy Annamalai university Annamalai Nagar Tamilnadu IndiaDepartment of Pharmacy Annamalai university Annamalai Nagar Tamilnadu IndiaABSTRACT - Effective targeted drug delivery systems have been a dream for a long time, but it has been largely frustrated by the complex chemistry that is involved in the development of new systems. The invention of nanosponges has become a significant step toward overcoming these problems. Nanosponges are tiny sponges with a size of about a virus, which can be filled with a wide variety of drugs. These tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner. Because the drug can be released at the specific target site instead of circulating throughout the body it will be more effective for a particular given dosage. Another important character of these sponges is their aqueous solubility; this allows the use of these systems effectively for drugs with poor solubility. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/12535 |
spellingShingle | Selvamuthukumar S Anandam S Kannan Krishnamoorthy Manavalan Rajappan Nanosponges: A Novel Class of Drug Delivery System - Review Journal of Pharmacy & Pharmaceutical Sciences |
title | Nanosponges: A Novel Class of Drug Delivery System - Review |
title_full | Nanosponges: A Novel Class of Drug Delivery System - Review |
title_fullStr | Nanosponges: A Novel Class of Drug Delivery System - Review |
title_full_unstemmed | Nanosponges: A Novel Class of Drug Delivery System - Review |
title_short | Nanosponges: A Novel Class of Drug Delivery System - Review |
title_sort | nanosponges a novel class of drug delivery system review |
url | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/12535 |
work_keys_str_mv | AT selvamuthukumars nanospongesanovelclassofdrugdeliverysystemreview AT anandams nanospongesanovelclassofdrugdeliverysystemreview AT kannankrishnamoorthy nanospongesanovelclassofdrugdeliverysystemreview AT manavalanrajappan nanospongesanovelclassofdrugdeliverysystemreview |