Nanosponges: A Novel Class of Drug Delivery System - Review

ABSTRACT - Effective targeted drug delivery systems have been a dream for a long time, but it has been largely frustrated by the complex chemistry that is involved in the development of new systems. The invention of nanosponges has become a significant step toward overcoming these problems. Nanospon...

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Main Authors: Selvamuthukumar S, Anandam S, Kannan Krishnamoorthy, Manavalan Rajappan
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/12535
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author Selvamuthukumar S
Anandam S
Kannan Krishnamoorthy
Manavalan Rajappan
author_facet Selvamuthukumar S
Anandam S
Kannan Krishnamoorthy
Manavalan Rajappan
author_sort Selvamuthukumar S
collection DOAJ
description ABSTRACT - Effective targeted drug delivery systems have been a dream for a long time, but it has been largely frustrated by the complex chemistry that is involved in the development of new systems. The invention of nanosponges has become a significant step toward overcoming these problems. Nanosponges are tiny sponges with a size of about a virus, which can be filled with a wide variety of drugs. These tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner. Because the drug can be released at the specific target site instead of circulating throughout the body it will be more effective for a particular given dosage. Another important character of these sponges is their aqueous solubility; this allows the use of these systems effectively for drugs with poor solubility. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
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spelling doaj.art-760411eafd384cc58134fc071bee81842023-08-02T04:46:40ZengFrontiers Media S.A.Journal of Pharmacy & Pharmaceutical Sciences1482-18262012-01-0115110.18433/J3K308Nanosponges: A Novel Class of Drug Delivery System - ReviewSelvamuthukumar S0Anandam S1Kannan KrishnamoorthyManavalan RajappanDepartment of Pharmacy Annamalai university Annamalai Nagar Tamilnadu IndiaDepartment of Pharmacy Annamalai university Annamalai Nagar Tamilnadu IndiaABSTRACT - Effective targeted drug delivery systems have been a dream for a long time, but it has been largely frustrated by the complex chemistry that is involved in the development of new systems. The invention of nanosponges has become a significant step toward overcoming these problems. Nanosponges are tiny sponges with a size of about a virus, which can be filled with a wide variety of drugs. These tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner. Because the drug can be released at the specific target site instead of circulating throughout the body it will be more effective for a particular given dosage. Another important character of these sponges is their aqueous solubility; this allows the use of these systems effectively for drugs with poor solubility. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/12535
spellingShingle Selvamuthukumar S
Anandam S
Kannan Krishnamoorthy
Manavalan Rajappan
Nanosponges: A Novel Class of Drug Delivery System - Review
Journal of Pharmacy & Pharmaceutical Sciences
title Nanosponges: A Novel Class of Drug Delivery System - Review
title_full Nanosponges: A Novel Class of Drug Delivery System - Review
title_fullStr Nanosponges: A Novel Class of Drug Delivery System - Review
title_full_unstemmed Nanosponges: A Novel Class of Drug Delivery System - Review
title_short Nanosponges: A Novel Class of Drug Delivery System - Review
title_sort nanosponges a novel class of drug delivery system review
url https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/12535
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AT kannankrishnamoorthy nanospongesanovelclassofdrugdeliverysystemreview
AT manavalanrajappan nanospongesanovelclassofdrugdeliverysystemreview