Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study
Objectives This study aims to evaluate the effect of congenital ectopia lentis (CEL) on functional vision and eye-related quality of life (ER-QOL) in children and their families using the Paediatric Eye Questionnaire (PedEyeQ).Design A questionnaire survey administered via in-person interviews of pa...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2023-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/12/e075222.full |
| _version_ | 1797370013312614400 |
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| author | Guangming Jin Minjie Zou Xinyu Zhang Charlotte Aimee Young Danying Zheng Siyuan Liu Xiaolin Liang Yiyuan Ma Lirong Ling |
| author_facet | Guangming Jin Minjie Zou Xinyu Zhang Charlotte Aimee Young Danying Zheng Siyuan Liu Xiaolin Liang Yiyuan Ma Lirong Ling |
| author_sort | Guangming Jin |
| collection | DOAJ |
| description | Objectives This study aims to evaluate the effect of congenital ectopia lentis (CEL) on functional vision and eye-related quality of life (ER-QOL) in children and their families using the Paediatric Eye Questionnaire (PedEyeQ).Design A questionnaire survey administered via in-person interviews of patients with CEL and their parents.Participants 51 children with CEL and 53 visually normal controls accompanied by 1 parent completed the survey questionnaires for the study from March 2022 to September 2022.Outcome measures PedEyeQ domain scores. Functional vision and ER-QOL of children and their families were evaluated by calculating and comparing the Rasch domain scores of the PedEyeQ.Results PedEyeQ domain scores were significantly worse with CEL compared with controls (p<0.01 for each), with the exception of the Proxy Social domain among children aged 0–4 years (p=0.283). Child PedEyeQ greatest differences were in the functional vision domain (5–11 years, −20 points (95% CI −27 to −12)) and frustration/worry domain (12–17 years, −41 (95% CI −37 to −6)). Proxy PedEyeQ greatest differences were in the functional vision domain (0–4 years, −34 (95% CI −45 to −22)) and frustration/worry domain (5–11 years, −27 (95% CI −39 to −14); 12–17 years, −37(95% CI (−48 to −26))). Parent PedEyeQ greatest difference was in the ‘worry about child’s eye condition’ (−57 (95% CI (−63 to −51))).Conclusions In this study, children with CEL had reduced functional vision and ER-QOL compared with controls. Parents of children with CEL also experience reduced quality of life. |
| first_indexed | 2024-03-08T17:55:17Z |
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| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-03-08T17:55:17Z |
| publishDate | 2023-12-01 |
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| series | BMJ Open |
| spelling | doaj.art-7605faa9e22140f2be8419e37a2b04d52024-01-02T05:25:07ZengBMJ Publishing GroupBMJ Open2044-60552023-12-01131210.1136/bmjopen-2023-075222Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional studyGuangming Jin0Minjie Zou1Xinyu Zhang2Charlotte Aimee Young3Danying Zheng4Siyuan Liu5Xiaolin Liang6Yiyuan Ma7Lirong Ling8State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China1 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, Guangdong, ChinaAlbany Medical College, Albany, New York, USAState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, Guangdong, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, Guangdong, ChinaSchool of Law and Sociology, Xihua University, Chengdu, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, ChinaObjectives This study aims to evaluate the effect of congenital ectopia lentis (CEL) on functional vision and eye-related quality of life (ER-QOL) in children and their families using the Paediatric Eye Questionnaire (PedEyeQ).Design A questionnaire survey administered via in-person interviews of patients with CEL and their parents.Participants 51 children with CEL and 53 visually normal controls accompanied by 1 parent completed the survey questionnaires for the study from March 2022 to September 2022.Outcome measures PedEyeQ domain scores. Functional vision and ER-QOL of children and their families were evaluated by calculating and comparing the Rasch domain scores of the PedEyeQ.Results PedEyeQ domain scores were significantly worse with CEL compared with controls (p<0.01 for each), with the exception of the Proxy Social domain among children aged 0–4 years (p=0.283). Child PedEyeQ greatest differences were in the functional vision domain (5–11 years, −20 points (95% CI −27 to −12)) and frustration/worry domain (12–17 years, −41 (95% CI −37 to −6)). Proxy PedEyeQ greatest differences were in the functional vision domain (0–4 years, −34 (95% CI −45 to −22)) and frustration/worry domain (5–11 years, −27 (95% CI −39 to −14); 12–17 years, −37(95% CI (−48 to −26))). Parent PedEyeQ greatest difference was in the ‘worry about child’s eye condition’ (−57 (95% CI (−63 to −51))).Conclusions In this study, children with CEL had reduced functional vision and ER-QOL compared with controls. Parents of children with CEL also experience reduced quality of life.https://bmjopen.bmj.com/content/13/12/e075222.full |
| spellingShingle | Guangming Jin Minjie Zou Xinyu Zhang Charlotte Aimee Young Danying Zheng Siyuan Liu Xiaolin Liang Yiyuan Ma Lirong Ling Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study BMJ Open |
| title | Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study |
| title_full | Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study |
| title_fullStr | Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study |
| title_full_unstemmed | Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study |
| title_short | Evaluation of functional vision and eye-related quality of life in children with congenital ectopia lentis: a prospective cross-sectional study |
| title_sort | evaluation of functional vision and eye related quality of life in children with congenital ectopia lentis a prospective cross sectional study |
| url | https://bmjopen.bmj.com/content/13/12/e075222.full |
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