Alteration of autophagosomal proteins (LC3, GABARAP and GATE-16) in Lewy body disease

Alteration of autophagosomal proteins (LC3, GABARAP and GATE-16) in Lewy body disease

Macroautophagy is a dynamic process whereby cytoplasmic molecules are sequestered within autophagosomes. Based on amino acid similarity, there exist two groups of mammalian autophagy-related gene (Atg) 8 homologues [microtubule-associated protein 1 light chain 3 (LC3) and γ-aminobutyric-acid type A...

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Bibliographic Details
Main Authors: Kunikazu Tanji, Fumiaki Mori, Akiyoshi Kakita, Hitoshi Takahashi, Koichi Wakabayashi
Format: Article
Language:English
Published: Elsevier 2011-09-01
Series:Neurobiology of Disease
Subjects:
Autophagosome
Dementia with Lewy bodies
Parkinson's disease
LC3
GABARAP
GATE-16
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111001914

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