THE ROLE OF MYOKINES INTERSTITIAL INTERACTION AND REGULATION OF METABOLISM: A REVIEW OF LITERATURE

Myokines are hormone-like acting molecules produced in skeletal muscles during and immediately after exercise. They affect both paracrine (inside the muscles themselves) and endocrine manner (in adipose tissue, liver, endothelium, skin, mucosa etc.) implementing different effects on target tissues,...

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Main Authors: T T Tsoriev, Zh E White, L Ya Rozhinskaya
Format: Article
Language:English
Published: Endocrinology Research Centre 2016-12-01
Series:Остеопороз и остеопатии
Online Access:https://endojournals.ru/index.php/osteo/article/view/8943
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author T T Tsoriev
Zh E White
L Ya Rozhinskaya
author_facet T T Tsoriev
Zh E White
L Ya Rozhinskaya
author_sort T T Tsoriev
collection DOAJ
description Myokines are hormone-like acting molecules produced in skeletal muscles during and immediately after exercise. They affect both paracrine (inside the muscles themselves) and endocrine manner (in adipose tissue, liver, endothelium, skin, mucosa etc.) implementing different effects on target tissues, mainly through regulation of metabolic processes (such as glucose and lipid metabolism, growth and division of neurons and endothelial cells and others). The examination of myokines is of great interest for researchers of different medicine departments, particularly for endocrinologists, because of myokines’ involvement in pathogenesis of abdominal and visceral obesity, diabetes mellitus type 2 and cardiovascular diseases that are all the components of metabolic syndrome. The most important issue for clinicians is a possibility of future therapeutic implication of the myokine’s signal pathways in treatment of widespread metabolic disorders.
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spelling doaj.art-76080e7137444a34812b1eea2e4ec6332022-12-21T22:41:08ZengEndocrinology Research CentreОстеопороз и остеопатии2072-26802311-07162016-12-01191283410.14341/osteo2016128-347988THE ROLE OF MYOKINES INTERSTITIAL INTERACTION AND REGULATION OF METABOLISM: A REVIEW OF LITERATURET T Tsoriev0Zh E White1L Ya Rozhinskaya2ФГБУ «Эндокринологический научный центр» Минздрава РоссииФГБУ «Эндокринологический научный центр» Минздрава РоссииФГБУ «Эндокринологический научный центр» Минздрава РоссииMyokines are hormone-like acting molecules produced in skeletal muscles during and immediately after exercise. They affect both paracrine (inside the muscles themselves) and endocrine manner (in adipose tissue, liver, endothelium, skin, mucosa etc.) implementing different effects on target tissues, mainly through regulation of metabolic processes (such as glucose and lipid metabolism, growth and division of neurons and endothelial cells and others). The examination of myokines is of great interest for researchers of different medicine departments, particularly for endocrinologists, because of myokines’ involvement in pathogenesis of abdominal and visceral obesity, diabetes mellitus type 2 and cardiovascular diseases that are all the components of metabolic syndrome. The most important issue for clinicians is a possibility of future therapeutic implication of the myokine’s signal pathways in treatment of widespread metabolic disorders.https://endojournals.ru/index.php/osteo/article/view/8943
spellingShingle T T Tsoriev
Zh E White
L Ya Rozhinskaya
THE ROLE OF MYOKINES INTERSTITIAL INTERACTION AND REGULATION OF METABOLISM: A REVIEW OF LITERATURE
Остеопороз и остеопатии
title THE ROLE OF MYOKINES INTERSTITIAL INTERACTION AND REGULATION OF METABOLISM: A REVIEW OF LITERATURE
title_full THE ROLE OF MYOKINES INTERSTITIAL INTERACTION AND REGULATION OF METABOLISM: A REVIEW OF LITERATURE
title_fullStr THE ROLE OF MYOKINES INTERSTITIAL INTERACTION AND REGULATION OF METABOLISM: A REVIEW OF LITERATURE
title_full_unstemmed THE ROLE OF MYOKINES INTERSTITIAL INTERACTION AND REGULATION OF METABOLISM: A REVIEW OF LITERATURE
title_short THE ROLE OF MYOKINES INTERSTITIAL INTERACTION AND REGULATION OF METABOLISM: A REVIEW OF LITERATURE
title_sort role of myokines interstitial interaction and regulation of metabolism a review of literature
url https://endojournals.ru/index.php/osteo/article/view/8943
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