A retrospective analysis of pain and opioid usage in head and neck free flap reconstruction

Abstract Objectives Investigate opioid usage and postoperative pain in patients undergoing head and neck free flap surgery. Methods A retrospective review of 100 consecutive patients undergoing head and neck free flap reconstruction at two academic centers was performed. Data captured included demog...

Full description

Bibliographic Details
Main Authors: Parhom Towfighi, Alison Hill, Jason R. Crossley, Amanda Walsh, James A. Leonard, Jonathan P. Giurintano, Matthew L. Pierce, Michael J. Reilly
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:World Journal of Otorhinolaryngology-Head and Neck Surgery
Subjects:
Online Access:https://doi.org/10.1002/wjo2.87
_version_ 1827915448250793984
author Parhom Towfighi
Alison Hill
Jason R. Crossley
Amanda Walsh
James A. Leonard
Jonathan P. Giurintano
Matthew L. Pierce
Michael J. Reilly
author_facet Parhom Towfighi
Alison Hill
Jason R. Crossley
Amanda Walsh
James A. Leonard
Jonathan P. Giurintano
Matthew L. Pierce
Michael J. Reilly
author_sort Parhom Towfighi
collection DOAJ
description Abstract Objectives Investigate opioid usage and postoperative pain in patients undergoing head and neck free flap surgery. Methods A retrospective review of 100 consecutive patients undergoing head and neck free flap reconstruction at two academic centers was performed. Data captured included demographics, postoperative inpatient pain, pain at postoperative visits, morphine equivalent doses (MEDs) administration, medication history, and comorbidities. Data were analyzed using regression models, χ2 tests, and student's t‐tests. Results Seventy‐three percent of patients were discharged with opioid medication, with over half (53.4%) continuing to take opioids at their second postoperative visit, and over one‐third (34.2%) continuing to take them around 4‐month postoperatively. One out of every five (20.3%) opioid‐naïve patients chronically took opioids postoperatively. There was a poor association between inpatient postoperative pain scores and daily MEDs administered (R2 = 0.13, 0.17, and 0.22 in postoperative Days 3, 5, and 7, respectively). Neither preoperative radiotherapy nor postoperative complications were associated with an increase in opioid usage. Conclusions For patients undergoing head and neck free flap operations, opioid medications are commonly used for postoperative analgesia. This practice may increase the chance an opioid‐naïve patient uses opioids chronically. We found a poor association between MEDs administered and patient‐reported pain scores, which suggests that standardized protocols aimed at optimizing analgesia while reducing opioid administration may be warranted. Level of Evidence: 3 (Retrospective cohort study).
first_indexed 2024-03-13T02:59:44Z
format Article
id doaj.art-76092e3d8b5540edb6b16125dc623d15
institution Directory Open Access Journal
issn 2095-8811
2589-1081
language English
last_indexed 2024-03-13T02:59:44Z
publishDate 2023-06-01
publisher Wiley
record_format Article
series World Journal of Otorhinolaryngology-Head and Neck Surgery
spelling doaj.art-76092e3d8b5540edb6b16125dc623d152023-06-27T14:52:59ZengWileyWorld Journal of Otorhinolaryngology-Head and Neck Surgery2095-88112589-10812023-06-019215315910.1002/wjo2.87A retrospective analysis of pain and opioid usage in head and neck free flap reconstructionParhom Towfighi0Alison Hill1Jason R. Crossley2Amanda Walsh3James A. Leonard4Jonathan P. Giurintano5Matthew L. Pierce6Michael J. Reilly7Georgetown University School of Medicine Washington District of Columbia USAGeorgetown University School of Medicine Washington District of Columbia USADepartment of Otolaryngology—Head and Neck Surgery Medstar Georgetown Washington District of Columbia USADepartment of Otolaryngology—Head and Neck Surgery Medstar Georgetown Washington District of Columbia USADepartment of Otolaryngology—Head and Neck Surgery Medstar Georgetown Washington District of Columbia USADepartment of Otolaryngology—Head and Neck Surgery Medstar Georgetown Washington District of Columbia USADepartment of Otolaryngology—Head and Neck Surgery Medstar Georgetown Washington District of Columbia USADepartment of Otolaryngology—Head and Neck Surgery Medstar Georgetown Washington District of Columbia USAAbstract Objectives Investigate opioid usage and postoperative pain in patients undergoing head and neck free flap surgery. Methods A retrospective review of 100 consecutive patients undergoing head and neck free flap reconstruction at two academic centers was performed. Data captured included demographics, postoperative inpatient pain, pain at postoperative visits, morphine equivalent doses (MEDs) administration, medication history, and comorbidities. Data were analyzed using regression models, χ2 tests, and student's t‐tests. Results Seventy‐three percent of patients were discharged with opioid medication, with over half (53.4%) continuing to take opioids at their second postoperative visit, and over one‐third (34.2%) continuing to take them around 4‐month postoperatively. One out of every five (20.3%) opioid‐naïve patients chronically took opioids postoperatively. There was a poor association between inpatient postoperative pain scores and daily MEDs administered (R2 = 0.13, 0.17, and 0.22 in postoperative Days 3, 5, and 7, respectively). Neither preoperative radiotherapy nor postoperative complications were associated with an increase in opioid usage. Conclusions For patients undergoing head and neck free flap operations, opioid medications are commonly used for postoperative analgesia. This practice may increase the chance an opioid‐naïve patient uses opioids chronically. We found a poor association between MEDs administered and patient‐reported pain scores, which suggests that standardized protocols aimed at optimizing analgesia while reducing opioid administration may be warranted. Level of Evidence: 3 (Retrospective cohort study).https://doi.org/10.1002/wjo2.87free flap reconstructionhead and neckmultimodal analgesiaopioidspostoperative pain
spellingShingle Parhom Towfighi
Alison Hill
Jason R. Crossley
Amanda Walsh
James A. Leonard
Jonathan P. Giurintano
Matthew L. Pierce
Michael J. Reilly
A retrospective analysis of pain and opioid usage in head and neck free flap reconstruction
World Journal of Otorhinolaryngology-Head and Neck Surgery
free flap reconstruction
head and neck
multimodal analgesia
opioids
postoperative pain
title A retrospective analysis of pain and opioid usage in head and neck free flap reconstruction
title_full A retrospective analysis of pain and opioid usage in head and neck free flap reconstruction
title_fullStr A retrospective analysis of pain and opioid usage in head and neck free flap reconstruction
title_full_unstemmed A retrospective analysis of pain and opioid usage in head and neck free flap reconstruction
title_short A retrospective analysis of pain and opioid usage in head and neck free flap reconstruction
title_sort retrospective analysis of pain and opioid usage in head and neck free flap reconstruction
topic free flap reconstruction
head and neck
multimodal analgesia
opioids
postoperative pain
url https://doi.org/10.1002/wjo2.87
work_keys_str_mv AT parhomtowfighi aretrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT alisonhill aretrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT jasonrcrossley aretrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT amandawalsh aretrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT jamesaleonard aretrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT jonathanpgiurintano aretrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT matthewlpierce aretrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT michaeljreilly aretrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT parhomtowfighi retrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT alisonhill retrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT jasonrcrossley retrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT amandawalsh retrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT jamesaleonard retrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT jonathanpgiurintano retrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT matthewlpierce retrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction
AT michaeljreilly retrospectiveanalysisofpainandopioidusageinheadandneckfreeflapreconstruction